Future perspectives
NJ Abbott - Blood‐Brain Barrier in Drug Discovery: Optimizing …, 2015 - Wiley Online Library
Recent work has contributed to understanding of the physiology of the brain endothelial
cells forming the blood–brain barrier (BBB), and their interaction with the associated cells of …
cells forming the blood–brain barrier (BBB), and their interaction with the associated cells of …
Brain endothelial cell-cell junctions: how to “open” the blood brain barrier
SM Stamatovic, RF Keep… - Current …, 2008 - ingentaconnect.com
The blood-brain barrier (BBB) is a highly specialized structural and biochemical barrier that
regulates the entry of blood-borne molecules into brain, and preserves ionic homeostasis …
regulates the entry of blood-borne molecules into brain, and preserves ionic homeostasis …
Morphogens and blood-brain barrier function in health and disease
NR Wevers, HE de Vries - Tissue barriers, 2016 - Taylor & Francis
The microvasculature of the brain forms a protective blood-brain barrier (BBB) that ensures a
homeostatic environment for the central nervous system (CNS), which is essential for …
homeostatic environment for the central nervous system (CNS), which is essential for …
Engaging neuroscience to advance translational research in brain barrier biology
The delivery of many potentially therapeutic and diagnostic compounds to specific areas of
the brain is restricted by brain barriers, of which the most well known are the blood–brain …
the brain is restricted by brain barriers, of which the most well known are the blood–brain …
Looking at the blood–brain barrier: molecular anatomy and possible investigation approaches
FL Cardoso, D Brites, MA Brito - Brain research reviews, 2010 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the
central nervous system that strictly controls the exchanges between the blood and brain …
central nervous system that strictly controls the exchanges between the blood and brain …
The blood–brain barrier: an overview: structure, regulation, and clinical implications
P Ballabh, A Braun, M Nedergaard - Neurobiology of disease, 2004 - Elsevier
The blood–brain barrier (BBB) is a diffusion barrier, which impedes influx of most
compounds from blood to brain. Three cellular elements of the brain microvasculature …
compounds from blood to brain. Three cellular elements of the brain microvasculature …
Blood–brain barrier: Recent developments and clinical correlations
EE Benarroch - Neurology, 2012 - AAN Enterprises
Neural survival and signaling within the CNS require a highly controlled microenvironment
that depends on the normal function of a neurovascular unit, which includes several …
that depends on the normal function of a neurovascular unit, which includes several …
Structure and function of the blood–brain barrier
NJ Abbott, AAK Patabendige, DEM Dolman… - Neurobiology of …, 2010 - Elsevier
Neural signalling within the central nervous system (CNS) requires a highly controlled
microenvironment. Cells at three key interfaces form barriers between the blood and the …
microenvironment. Cells at three key interfaces form barriers between the blood and the …
Blood–brain barrier in disease states
The notion that a static blood–brain barrier (BBB) controls the rapidly changing brain
environment is obsolete. Not only have we recognized the role of the BBB in maintenance of …
environment is obsolete. Not only have we recognized the role of the BBB in maintenance of …
Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview
The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …