The PI3K-Akt-mTOR and associated signaling pathways as molecular drivers of immune-mediated inflammatory skin diseases: update on therapeutic strategy using …
The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …
[HTML][HTML] Recent updates on the involvement of PI3K/AKT/mTOR molecular cascade in the pathogenesis of hyperproliferative skin disorders
L Mercurio, C Albanesi, S Madonna - Frontiers in Medicine, 2021 - frontiersin.org
PhosphoInositide-3 Kinase (PI3K) represents a family of different classes of kinases which
control multiple biological processes in mammalian cells, such as cell growth, proliferation …
control multiple biological processes in mammalian cells, such as cell growth, proliferation …
Predominant role of mTOR signaling in skin diseases with therapeutic potential
F Karagianni, A Pavlidis, LS Malakou, C Piperi… - International Journal of …, 2022 - mdpi.com
The serine/threonine kinase mechanistic target of rapamycin (mTOR) plays a pivotal role in
the regulation of cell proliferation, survival, and motility in response to availability of energy …
the regulation of cell proliferation, survival, and motility in response to availability of energy …
[PDF][PDF] Phosphoinositide-3 kinase/protein kinase-B/mammalian target of rapamycin pathway in psoriasis pathogenesis. A potential therapeutic target?
T Huang, X Lin, X Meng, M Lin - Acta dermato …, 2014 - medicaljournalssweden.se
Psoriasis is a common chronic inflammatory disease of the skin. Its pathogenesis has not
been completely elucidated. Phosphoinositide-3 kinase/protein kinase-B/mammalian target …
been completely elucidated. Phosphoinositide-3 kinase/protein kinase-B/mammalian target …
Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents …
The mammalian or mechanistic target of rapamycin (mTOR) and associated phosphatidyl-
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …
mTOR signaling cascade in psoriatic disease: double kinase mTOR inhibitor a novel therapeutic target
SK Raychaudhuri… - Indian journal of …, 2014 - journals.lww.com
In this short communication we are providing insight about the regulatory role of the
phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) kinase …
phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) kinase …
Phytochemical modulation of the Akt/mTOR pathway and its potential use in cutaneous disease
MS Leo, RK Sivamani - Archives of Dermatological Research, 2014 - Springer
The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth,
proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two …
proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two …
The PI3K/Akt pathway: emerging roles in skin homeostasis and a group of non-malignant skin disorders
Y Teng, Y Fan, J Ma, W Lu, N Liu, Y Chen, W Pan… - Cells, 2021 - mdpi.com
The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway regulates
cell proliferation, differentiation, and migration, along with angiogenesis and metabolism …
cell proliferation, differentiation, and migration, along with angiogenesis and metabolism …
Exploiting PI 3 K/m TOR signaling to accelerate epithelial wound healing
The molecular circuitries controlling the process of skin wound healing have gained new
significant insights in recent years. This knowledge is built on landmark studies on skin …
significant insights in recent years. This knowledge is built on landmark studies on skin …
Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies
The phosphoinositide 3-kinase/mammalian target of rapamycin/protein kinase B
(PI3K/mTOR/Akt) signaling pathway is central to a plethora of cellular mechanisms in a wide …
(PI3K/mTOR/Akt) signaling pathway is central to a plethora of cellular mechanisms in a wide …
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