Memory T cells form an essential part of immunological memory, which can last for years or
even a lifetime. Much experimental work has shown that the individual cells that make up the …

Peripheral CD4÷ lymphocytes can be subdivided into naive, effector and memory subsets
(T,, ble I). Naive T cells are resting pr,: cursors which have not encountered antigen (Ag) …

Mature T cells are produced in the thymus and released into the bloodstream in low
numbers. These cells are considered to be immunologically naıve until such time as they …

Immunological memory is manifested by the body's ability to enjoy long-term protection
against specific pathogens previously encountered through illness or vaccination. This …

Memory T cells constitute the most abundant lymphocyte population in the body for the
majority of a person's lifetime; however, our understanding of memory T cell generation …

Our understanding of memory T cell function in mice and men is to date in large part
restricted to the behavior of circulating memory T cells. Emerging evidence, however …

Memory T cells can be broadly divided into central memory and effector memory subsets,
which are endowed with different capacities to home to lymphoid or non-lymphoid tissues, to …

Immunological memory is a fundamental feature of vertebrate immune systems, providing
enhanced protection against previously encountered antigens. The established view has …

Pre-existing T cell memory provides substantial protection against viral, bacterial, and
parasitic infections. The generation of protective T cell memory constitutes a primary goal for …

Animal models have revealed the rules for the organization of mature T-cell pools. However,
in humans, little is known about memory T cells, which differ in lifespan and in the number of …