Context Individuals with monogenic diabetes due to inactivating glucokinase (GCK) variants
typically do not require treatment, except potentially during pregnancy. In pregnancy, fetal …

Background Mutations in the GCK gene cause Maturity Onset Diabetes of the Young (GCK-
MODY) by impairing glucose-sensing in pancreatic beta cells. During pregnancy, managing …

Aims To determine the fetal and maternal outcomes in pregnant women with Glucokinase‐
Maturity onset diabetes of the young (GCK‐MODY). Methods We studied the obstetric and …

Heterozygous loss-of-function variants of the glucokinase (GCK) gene are responsible for a
subtype of maturity-onset diabetes of the young (MODY). GCK-MODY is characterized by a …

Aims GCK-MODY is characterized by mild hyperglycemia. Treatment is not required outside
of pregnancy. During pregnancy, insulin treatment is recommended if second trimester fetal …

Aims/hypothesis In pregnancies where the mother has glucokinase-MODY (GCK-MODY),
fetal growth is determined by fetal genotype. When the fetus inherits a maternal pathogenic …

Precise differentiation of glucokinase (GCK) monogenic diabetes from gestational diabetes
mellitus (GDM) is critical for accurate management of the pregnancy outcome. We screened …

OBJECTIVE Identifying glucokinase monogenic diabetes (GCK-MODY) in pregnancy is
important, as management is different from management for other forms of gestational …

Background: GCK gene variants have been reported to be associated with gestational
diabetes mellitus (GDM) in the Caucasian population. There are no reports exploring this …

Context Challenges exist in the management of Glucokinase–maturity-onset diabetes of the
young (GCK-MODY), especially during pregnancy. Objective This work aimed to evaluate …