Recent systems studies of gene expression have begun to dissect the layers of regulation
that underlie the eukaryotic transcriptome, the combined consequence of transcriptional and …

Experiments reported over the past several years, including genome-wide microarray
approaches, have demonstrated that many eukaryotic RNA-binding proteins (RBPs) …

Post-transcriptional regulation of gene expression plays important roles in diverse cellular
processes such as development, metabolism and cancer progression. Whereas many …

Gene expression is a highly controlled process which is known to occur at several levels in
eukaryotic organisms. Although messenger RNAs have been traditionally viewed as passive …

The ribonome is the total cellular complement of RNAs and their regulatory factors
functioning dynamically in time and space within ribonucleoprotein complexes. We theorize …

RNA-binding proteins (RBPs) play important roles in the posttranscriptional control of gene
expression. However, our understanding of how RBPs interact with each other at different …

Gene expression is regulated by a complex series of events that take place both at the
transcriptional and post-transcriptional levels. The mechanisms and factors involved in …

Gene expression is regulated at multiple levels, and cells need to integrate and coordinate
different layers of control to implement the information in the genome. Post-transcriptional …

In eukaryotic organisms, gene expression requires an additional level of coordination that
links transcriptional and posttranslational processes. Messenger RNAs have traditionally …

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