[68Ga]Ga-Pentixafor for PET Imaging of Vascular Expression of CXCR-4 as a Marker of Arterial Inflammation in HIV-Infected Patients: A Comparison with 18F[FDG] …
IO Lawal, GO Popoola, J Mahapane, J Kaufmann… - Biomolecules, 2020 - mdpi.com
People living with human immunodeficiency virus (PLHIV) have excess risk of
atherosclerotic cardiovascular disease (ASCVD). Arterial inflammation is the hallmark of …
atherosclerotic cardiovascular disease (ASCVD). Arterial inflammation is the hallmark of …
18FDG PET-CT imaging detects arterial inflammation and early atherosclerosis in HIV-infected adults with cardiovascular disease risk factors
KE Yarasheski, E Laciny, ET Overton, DN Reeds… - Journal of …, 2012 - Springer
Background Persistent vascular inflammation has been implicated as an important cause for
a higher prevalence of cardiovascular disease (CVD) in HIV-infected adults. In several …
a higher prevalence of cardiovascular disease (CVD) in HIV-infected adults. In several …
Radionuclide imaging of inflammation in atherosclerotic vascular disease among people living with HIV infection: current practice and future perspective
IO Lawal, AO Ankrah, AC Stoltz… - European Journal of Hybrid …, 2019 - Springer
People living with human immunodeficiency virus (HIV) infection have twice the risk of
atherosclerotic vascular disease compared with non-infected individuals. Inflammation plays …
atherosclerotic vascular disease compared with non-infected individuals. Inflammation plays …
HIV infection and arterial inflammation assessed by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET): a prospective cross-sectional study
A Knudsen, AMF Hag, A Loft, E von Benzon… - Journal of Nuclear …, 2015 - Elsevier
Background HIV-infected patients are at increased risk of myocardial infarction and arterial
inflammation has been suggested as a pathophysiological explanation. We compared the …
inflammation has been suggested as a pathophysiological explanation. We compared the …
Imaging inflammation in atherosclerosis with CXCR4-directed 68Ga-pentixafor PET/CT: correlation with 18F-FDG PET/CT
M Kircher, J Tran-Gia, L Kemmer, X Zhang… - Journal of Nuclear …, 2020 - Soc Nuclear Med
CXC motif chemokine receptor 4 (CXCR4) is expressed on the surface of various cell types
involved in atherosclerosis, with a particularly rich receptor expression on macrophages and …
involved in atherosclerosis, with a particularly rich receptor expression on macrophages and …
Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people
N Taglieri, R Bonfiglioli, I Bon, P Malosso… - Journal of Nuclear …, 2022 - Elsevier
Abstract Study Design To compare arterial inflammation (AI) between people living with HIV
(PLWH) and uninfected people as assessed by 18 F-Fluorodeoxyglucose (18 F-FDG) …
(PLWH) and uninfected people as assessed by 18 F-Fluorodeoxyglucose (18 F-FDG) …
18Fluoride-based molecular imaging of coronary atherosclerosis in HIV infected patients
G Guaraldi, J Milic, N Prandini, G Ligabue, F Esposito… - Atherosclerosis, 2020 - Elsevier
Background and aims Molecular imaging with 18 Fluorodeoxyglucose (FDG) and 18 F-
sodium-fluoride (NaF) captures arterial inflammation and micro-calcification and can reveal …
sodium-fluoride (NaF) captures arterial inflammation and micro-calcification and can reveal …
Imaging the cytokine receptor CXCR4 in atherosclerotic plaques with the radiotracer 68Ga-pentixafor for PET
F Hyafil, J Pelisek, I Laitinen, M Schottelius… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68Ga-pentixafor is a radiotracer for PET that binds with nanomolar affinity to CXCR4. The
CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study …
CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study …
Arterial inflammation in patients with HIV
Context Cardiovascular disease is increased in patients with human immunodeficiency virus
(HIV), but the specific mechanisms are unknown. Objective To assess arterial wall …
(HIV), but the specific mechanisms are unknown. Objective To assess arterial wall …
Clinical molecular imaging of chemokine receptor CXCR4 expression in atherosclerotic plaque using 68Ga-pentixafor PET: correlation with cardiovascular risk factors …
D Weiberg, JT Thackeray, G Daum… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The CXC-motif chemokine receptor 4 (CXCR4) represents a promising target for molecular
imaging of different CXCR4-positive cell types in cardiovascular diseases such as …
imaging of different CXCR4-positive cell types in cardiovascular diseases such as …
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