Background and purpose Toluene diisocyanate (TDI)-induced asthma is characterized by
mixed inflammation dominated by neutrophils, and is refractory to steroid treatment …

Neutrophilic asthma (NA) is a distinct airway inflammation disease with prominent neutrophil
infiltration. The role played by neutrophil extracellular traps (NETs) in NA, however, is quite …

The hypothesis of autoimmune involvement in asthma has received much recent interest.
Autoantibodies, such as anti-cytokeratin (CK) 18, anti-CK19, and anti-α-enolase antibodies …

Background Autophagy and neutrophil extracellular DNA traps (NET s) are implicated in
asthma; however, their roles in asthma pathogenesis have not been elucidated. Objectives …

Neutrophil extracellular traps (NETs) may play a critical role in smoking-related chronic
airway inflammation. However, the mechanism by which NETs induced by cigarette smoke …

Asthma is a common chronic respiratory disease that affects millions of people worldwide.
The incidence of asthma has continued to increase every year. Bronchial asthma involves a …

Objective: Asthma and chronic obstructive pulmonary disease (COPD) are representative
chronic inflammatory airway diseases responsible for a considerable burden of disease. In …

Asthma is a chronic inflammatory disease characterized by variable airflow limitation and
airway hyperresponsiveness. A plethora of immune and structural cells are involved in …

Rationale: Extracellular DNA (eDNA) and neutrophil extracellular traps (NETs) are
implicated in multiple inflammatory diseases. NETs mediate inflammasome activation and IL …

Neutrophil extracellular traps (NETs) were initially identified as an important antimicrobial
barrier to capture and kill microorganisms. Emerging evidence suggests that NETs play a …