Dystrophin is a 427 kDa sub-membrane cytoskeletal protein, associated with the inner
surface membrane and incorporated in a large macromolecular complex of proteins, the …

Dystrophin and its associated proteins were originally identified in skeletal muscle, where
the complex provides mechanical stabilization to the sarcolemma during contraction …

Since its first description in 1990, the dystrophin–glycoprotein complex has emerged as a
critical nexus for human muscular dystrophies arising from defects in a variety of distinct …

Dystrophin, the product of the Duchenne muscular dystrophy gene, is tightly associated with
the sarcolemmal membrane to a large glycoprotein complex. One function of the dystrophin …

The dystrophin-associated protein complex (DAPC) is necessary for maintaining the integrity
of the muscle cell plasma membrane and may also play a role in coordinating signaling …

Dystrophin plays an important role in skeletal muscle by linking the cytoskeleton and the
extracellular matrix. The amino terminus of dystrophin binds to actin and possibly other …

The dystrophin‐associated protein complex (DAPC), which links the cytoskeleton to the
extracellular matrix, is essential for muscle cell survival, and is defective in a wide range of …

The systematic bioanalytical characterization of the protein product of the DMD gene, which
is defective in the pediatric disorder Duchenne muscular dystrophy, led to the discovery of …

Dystrophin is one of a number of large cytoskeleton associated proteins that connect
between various cytoskeletal elements and often are tethered to the membrane through …

The identification and isolation of the gene that when altered causes Duchenne muscular
dystrophy (Hoffman et al., 1987) led to the characterization of dystrophin and the dystrophin …