Uric acid, the end-product of purine metabolism in humans, is not only a cause of gout, but
also may play roles in developing cardiovascular diseases such as hypertension, atrial …

This review summarizes recent published literature on the association between serum uric
acid and cardiovascular disease, a relationship which is complex and not fully elucidated …

Uric acid has long been associated with cardiovascular disease. Most epidemiological
evidence suggests a significant, graded, independent and specific association between the …

Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly
considered a true risk factor. Recent studies suggest that uric acid is biologically active and …

The relationship between uric acid and cardiovascular disease has been known since the
19th century, after that many authors reported the classical association of gout …

In recent years, serum uric acid (SUA) as a determinant of cardiovascular (CV) risk has
gained interest. Epidemiological, experimental and clinical data show that patients with …

The relationship between serum uric acid (SUA) and cardiovascular disease has been
controversial. Here we review recent literature assessing whether hyperuricemia is an …

Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …

During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …

Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has
recently been suggested to be associated with hypertension, coronary heart disease, heart …