A product of the adenovirus gene E1A is responsible for the stimulation of transcription from
six viral promoters as well as at least two cellular promoters. We have detected a HeLa cell …

We have previously shown that E1A‐mediated induction of the adenovirus E2 transcription
unit likely involves the posttranslational activation of a previously limiting cellular factor …

Previous experiments have demonstrated that adenovirus infection of human and mouse
cells leads to an E1A-dependent activation of the DNA-binding capacity of a cellular …

Transcription of the set of early adenovirus genes is subject to positive control by the viral
E1A gene. For one early viral gene, the E2 gene, this induction involves an increase in a …

Efficient transcription of the adenovirus E1a‐inducible E4 gene is mediated by an E1a‐
dependent enhancer in vivo. In vitro, the enhancer functions constitutively in the absence of …

The promoter-specific factor E2F interacts with critical regulatory sequences within the
adenovirus E2 promoter. In addition, the level of active factor increases markedly during a …

Utilizing deletion mutants of a plasmid containing the adenovirus E2 gene, an E1A-inducible
transcription unit, we determined the promoter sequences required for full expression in …

The adenovirus E4 gene encodes a trans-activating function that can stimulate the E2
promoter. E2 promoter sequences required for E4 trans-activation are identical to those …

Previous experiments have identified E4F, an inducible cellular factor that binds to
sequences in the adenovirus E4 promoter that are critical for E1A-dependent transcriptional …

We have examined the relationship between sequence-specific DNA-binding proteins that
activate transcription of E1A-inducible adenovirus early promoters. Factors previously …