Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

A genome-wide association study (GWAS) of prostate cancer in Kaiser Permanente health
plan members (7,783 cases, 38,595 controls; 80.3% non-Hispanic white, 4.9% African …

Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in
developed countries and the second leading cause of cancer mortality, yet little is known …

Background: Genome-wide association studies (GWAS) have identified numerous prostate
cancer susceptibility alleles, but these loci have been identified primarily in men of …

Prostate cancer incidence and mortality rates in African and African American men are
greatly elevated compared with other ethnicities. This disparity is likely explained by a …

Genome-wide association studies have identified multiple common alleles associated with
prostate cancer risk in populations of European ancestry. Testing these variants in other …

Background Genome-wide association studies do not always replicate well across
populations, limiting the generalizability of polygenic risk scores (PRS). Despite higher …

In search of common risk alleles for prostate cancer that could contribute to high rates of the
disease in men of African ancestry, we conducted a genome-wide association study, with …