[HTML][HTML] Dopaminergic dysregulation in syndromic autism spectrum disorders: insights from genetic mouse models

P Kosillo, HS Bateup - Frontiers in Neural Circuits, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by altered social
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately …

Modeling dopamine dysfunction in autism spectrum disorder: From invertebrates to vertebrates

GE DiCarlo, MT Wallace - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a highly heterogeneous neurodevelopmental
disorder characterized by deficits in social communication and by patterns of restricted …

The dopamine hypothesis of autism spectrum disorder revisited: current status and future prospects

D Pavăl, IV Micluția - Developmental neuroscience, 2021 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. Despite intensive research, its …

Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)

M Nguyen, A Roth, EJ Kyzar, MK Poudel… - Neurochemistry …, 2014 - Elsevier
Autism spectrum disorder (ASD) is a debilitating brain illness causing social deficits, delayed
development and repetitive behaviors. ASD is a heritable neurodevelopmental disorder with …

Excessive D1 dopamine receptor activation in the dorsal striatum promotes autistic-like behaviors

Y Lee, H Kim, JE Kim, JY Park, J Choi, JE Lee… - Molecular …, 2018 - Springer
The dopamine system has been characterized in motor function, goal-directed behaviors,
and rewards. Recent studies recognize various dopamine system genes as being …

[HTML][HTML] Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

GE DiCarlo, JI Aguilar, HJG Matthies… - The Journal of …, 2020 - Am Soc Clin Investig
The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT)
ensures the phasic nature of the DA signal, which underlies the ability of DA to encode …

A dopamine hypothesis of autism spectrum disorder

D Pavăl - Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …

[HTML][HTML] Increased dopamine type 2 gene expression in the dorsal striatum in individuals with autism spectrum disorder suggests alterations in indirect pathway …

C Brandenburg, JJ Soghomonian, K Zhang… - Frontiers in Cellular …, 2020 - frontiersin.org
Autism spectrum disorder (ASD) is behaviorally defined and diagnosed by delayed and/or
impeded language, stereotyped repetitive behaviors, and difficulties with social interactions …

[HTML][HTML] Striatal circuits as a common node for autism pathophysiology

MV Fuccillo - Frontiers in neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral …

[HTML][HTML] Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

OY Chao, SS Pathak, H Zhang, N Dunaway, JS Li… - Molecular brain, 2020 - Springer
The dopamine (DA) system has a profound impact on reward-motivated behavior and is
critically involved in neurodevelopmental disorders, such as autism spectrum disorder …