Verapamil stereoisomers induce antiproliferative effects in vascular smooth muscle cells via autophagy
JK Salabei, A Balakumaran, JC Frey, PJ Boor… - Toxicology and applied …, 2012 - Elsevier
Calcium channel blockers (CCBs) are important in the management of hypertension and
limit restenosis. Although CCB efficacy could derive from decreased blood pressure, other …
limit restenosis. Although CCB efficacy could derive from decreased blood pressure, other …
Dual mechanism of action of amlodipine in human vascular smooth muscle cells
O Stepien, Y Zhang, D Zhu, P Marche - Journal of hypertension, 2002 - journals.lww.com
Objectives It has been recently shown that calcium channel blockers (CCBs) could also
control smooth muscle cell (SMC) growth/reactivity through mechanisms that were unrelated …
control smooth muscle cell (SMC) growth/reactivity through mechanisms that were unrelated …
[PDF][PDF] Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers
J Menne, JK Park, R Agrawal, C Lindschau… - The FASEB …, 2006 - researchgate.net
In clinical studies, dihydropyridine channel blockers (CCBs) improve endothelial dysfunction
in hypertensive patients and in patients with manifest atherosclerosis. Long-acting third …
in hypertensive patients and in patients with manifest atherosclerosis. Long-acting third …
Fluvastatin Upregulates the α1C Subunit of CaV1.2 Channel Expression in Vascular Smooth Muscle Cells via RhoA and ERK/p38 MAPK Pathways
QF Ouyang, Y Han, ZH Lin, H Xie, CS Xu… - Disease …, 2014 - Wiley Online Library
Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of
vascular disorders such as atherosclerosis and restenosis. And this process has been …
vascular disorders such as atherosclerosis and restenosis. And this process has been …
Cilostazol promotes vascular smooth muscles cell differentiation through the cAMP response element-binding protein-dependent pathway
WJ Chen, YH Chen, KH Lin… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Cilostazol, a potent type 3 phosphodiesterase inhibitor, has recently been found
to reduce neointimal formation by inhibiting vascular smooth muscle cell (VSMC) …
to reduce neointimal formation by inhibiting vascular smooth muscle cell (VSMC) …
Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism
E Kania, B Pająk, J O'Prey, P Sierra Gonzalez… - The FEBS …, 2017 - Wiley Online Library
Verapamil, an L‐type calcium channel blocker, has been used successfully to treat
cardiovascular diseases. Interestingly, we have recently shown that treatment of cancer cells …
cardiovascular diseases. Interestingly, we have recently shown that treatment of cancer cells …
Vascular effects of calcium channel antagonists: new evidence
S Richard - Drugs, 2005 - Springer
Calcium channel antagonists have a well-established role in the management of
cardiovascular diseases. L-type calcium channels in vascular cells are a key therapeutic …
cardiovascular diseases. L-type calcium channels in vascular cells are a key therapeutic …
Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes
C Pushparaj, A Das, R Purroy, M Nager… - … International Journal of …, 2015 - Elsevier
Voltage-gated calcium channel blockers are widely used for the management of
cardiovascular diseases, however little is known about their effects on cardiac cells in vitro …
cardiovascular diseases, however little is known about their effects on cardiac cells in vitro …
The Cav3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice
BH Tzeng, YH Chen, CH Huang, SS Lin… - Cardiovascular …, 2012 - academic.oup.com
Aims Restenosis is an undesirable consequence following percutaneous vascular
interventions. However, the current strategy for preventing restenosis is inadequate. The aim …
interventions. However, the current strategy for preventing restenosis is inadequate. The aim …
Calcium channel blockers, apoptosis and cancer: is there a biologic relationship?
RP Mason - Journal of the American College of Cardiology, 1999 - jacc.org
Calcium channel blockers (CCBs) represent a chemically and pharmacologically diverse
group of agents that are widely used for the treatment of hypertension and angina. A small …
group of agents that are widely used for the treatment of hypertension and angina. A small …