It is unknown whether interactions between tuft cells and trigeminal sinonasal neurons
contribute to allergic disease. Intranasal administration of house dust mite or fungal …

Objective To review the latest discoveries regarding the role of tuft cells in the pathogenesis
of chronic rhinosinusitis (CRS) with nasal polyposis and asthma. Data Sources Reviews and …

The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

The olfactory neuroepithelium serves as a sensory organ for odors and is part of the nasal
mucosal barrier. Olfactory sensory neurons are surrounded and supported by epithelial …

Allergic conjunctivitis (AC), an allergen-induced ocular inflammatory disease, primarily
involves mast cells (MCs) and eosinophils. The role of neuroimmune mechanisms in AC …

Background: The epithelial immune regulation is an essential and protective feature of the
barrier function of the mucous membranes of the airways. Damage to the epithelial barrier …

Neutrophilic inflammation contributes to multiple chronic inflammatory airway diseases,
including asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), and is associated …

Exploring the Neuro-immune Mechanisms Underlying Nasal Hyperreactivity in Rhinitis and
Rhinosinusitis KU Leuven Biomedical Sciences Group Faculty of Medicine Department of …

Background Chronic rhinosinusitis (CRS) with nasal polyps (CRS w NP) is a chronic
inflammatory disease often accompanied by impairment of sense of smell. This symptom …

Chronic rhinosinusitis (CRS) is a common chronic nasal cavity and sinus disease, affecting
a growing number of individuals worldwide. Recent advances have shifted our …