[HTML][HTML] CC-486 maintenance after stem cell transplantation in patients with acute myeloid leukemia or myelodysplastic syndromes
M De Lima, B Oran, RE Champlin… - Biology of Blood and …, 2018 - Elsevier
Relapse is the main cause of treatment failure after allogeneic stem cell transplant (alloSCT)
in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Injectable …
in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Injectable …
[HTML][HTML] Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia
C Craddock, M Labopin, M Robin, J Finke… - …, 2016 - ncbi.nlm.nih.gov
Disease relapse is the most common cause of treatment failure after allogeneic stem cell
transplantation for acute myeloid leukemia and myelodysplastic syndromes, yet treatment …
transplantation for acute myeloid leukemia and myelodysplastic syndromes, yet treatment …
Maintenance therapy with low‐dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic …
BACKGROUND: Recurrence is a major cause of treatment failure after allogeneic
transplantation for acute myelogenous leukemia (AML) and myelodysplastic syndrome …
transplantation for acute myelogenous leukemia (AML) and myelodysplastic syndrome …
A phase 3 randomized study of 5-azacitidine maintenance vs observation after transplant in high-risk AML and MDS patients
This study investigated the efficacy and safety of azacitidine maintenance in the
posttransplant setting based on the encouraging phase 1/2 reports for azacitidine …
posttransplant setting based on the encouraging phase 1/2 reports for azacitidine …
Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes
G Garcia-Manero, SD Gore, S Kambhampati, B Scott… - Leukemia, 2016 - nature.com
CC-486, the oral formulation of azacitidine (AZA), is an epigenetic modifier and DNA
methyltransferase inhibitor in clinical development for treatment of hematologic …
methyltransferase inhibitor in clinical development for treatment of hematologic …
[HTML][HTML] Tolerability and clinical activity of post-transplantation azacitidine in patients allografted for acute myeloid leukemia treated on the RICAZA trial
Disease relapse is the major causes of treatment failure after allogeneic stem cell
transplantation (SCT) in patients with acute myeloid leukemia (AML). As well as …
transplantation (SCT) in patients with acute myeloid leukemia (AML). As well as …
[HTML][HTML] Treatment of acute myeloid leukemia or myelodysplastic syndrome relapse after allogeneic stem cell transplantation with azacitidine and donor lymphocyte …
T Schroeder, E Rachlis, G Bug, M Stelljes… - Biology of Blood and …, 2015 - Elsevier
To expand the current knowledge about azacitidine (Aza) and donor lymphocyte infusions
(DLI) as salvage therapy for relapse after allogeneic hematopoietic stem cell transplantation …
(DLI) as salvage therapy for relapse after allogeneic hematopoietic stem cell transplantation …
[HTML][HTML] Oral azacitidine maintenance therapy for acute myeloid leukemia in first remission
Background Although induction chemotherapy results in remission in many older patients
with acute myeloid leukemia (AML), relapse is common and overall survival is poor …
with acute myeloid leukemia (AML), relapse is common and overall survival is poor …
[HTML][HTML] The QUAZAR AML-001 maintenance trial: results of a phase III international, randomized, double-blind, placebo-controlled study of CC-486 (oral formulation …
Introduction: Many older patients (pts) with AML respond to intensive induction
chemotherapy (IC), but responses are often short-lived and overall survival (OS) is poor. The …
chemotherapy (IC), but responses are often short-lived and overall survival (OS) is poor. The …
Extended dosing with CC‐486 (oral azacitidine) in patients with myeloid malignancies
MR Savona, K Kolibaba, P Conkling… - American journal of …, 2018 - Wiley Online Library
Abstract CC‐486 (oral azacitidine) is an epigenetic modifier in clinical development for
treatment of hematological cancers. This study of extended CC‐486 dosing included …
treatment of hematological cancers. This study of extended CC‐486 dosing included …