Pathophysiology of delayed cerebral ischemia after subarachnoid hemorrhage: a review

WS Dodd, D Laurent, AS Dumont… - Journal of the …, 2021 - Am Heart Assoc
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer
subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many …

The pathophysiology of delayed cerebral ischemia

B Foreman - Journal of Clinical Neurophysiology, 2016 - journals.lww.com
Subarachnoid hemorrhage (SAH) affects 30,000 people in the Unites States alone each
year. Delayed cerebral ischemia occurs days after subarachnoid hemorrhage and …

Delayed cerebral ischemia after subarachnoid hemorrhage: beyond vasospasm and towards a multifactorial pathophysiology

JR Geraghty, FD Testai - Current atherosclerosis reports, 2017 - Springer
Abstract Purpose of Review Delayed cerebral ischemia (DCI) is common after subarachnoid
hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was …

Early brain injury after subarachnoid hemorrhage: incidence and mechanisms

DC Lauzier, K Jayaraman, JY Yuan, D Diwan… - Stroke, 2023 - Am Heart Assoc
Aneurysmal subarachnoid hemorrhage is a devastating condition causing significant
morbidity and mortality. While outcomes from subarachnoid hemorrhage have improved in …

Current management of delayed cerebral ischemia: update from results of recent clinical trials

S Brathwaite, RL Macdonald - Translational stroke research, 2014 - Springer
Subarachnoid hemorrhage (SAH) accounts for 5–7% of all strokes worldwide and is
associated with high mortality and morbidity. Even after surgical intervention, approximately …

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage

KP Budohoski, M Guilfoyle, A Helmy… - Journal of Neurology …, 2014 - jnnp.bmj.com
Cerebral vasospasm has traditionally been regarded as an important cause of delayed
cerebral ischaemia (DCI) which occurs after aneurysmal subarachnoid haemorrhage, and …

Vasospasm versus delayed cerebral ischemia as an outcome event in clinical trials and observational studies

MDI Vergouwen… - Neurocritical care, 2011 - Springer
Delayed cerebral ischemia occurs in about 30% of patients during the first 2 weeks after
subarachnoid hemorrhage, and can result in substantial disability and death. Research …

Mechanisms of early brain injury after subarachnoid hemorrhage

WJ Cahill, JH Calvert, JH Zhang - Journal of Cerebral Blood …, 2006 - journals.sagepub.com
Apoptosis is the term given to programmed cell death, which has been widely connected to
a number of intracranial pathologies including stroke, Alzheimer's disease, and more …

Subarachnoid hemorrhage: is it time for a new direction?

J Cahill, JH Zhang - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Despite recent advances in the treatment of patients after
subarachnoid hemorrhage, morbidity and mortality rates have failed to improve significantly …

Emerging markers of early brain injury and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage

F Al-Mufti, K Amuluru, B Smith, N Damodara… - World Neurosurgery, 2017 - Elsevier
Background Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage is
characterized by a highly complex pathophysiology and results in neurologic deterioration …