Personalized anti-cancer medicine is boosted by the recent development of molecular
diagnostics and molecularly targeted drugs requiring rapid and efficient ligation routes …

Drug delivery platforms comprising an anticancer drug bound to a fluorogenic dye are of
great importance for theranostics and personalized medicine. The existing platforms suffer …

We developed a real-time drug-reporting conjugate (CPT-SS-CyN) composed of a near-
infrared (NIR) fluorescent cyanine-amine dye (CyN), a disulfide linker, and a model …

Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The
conjugates include Several cyanine dyes with a variety of bis-and tetrakis (carboxylic acid) …

Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …

Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The
conjugates include several cyanine dyes with a variety of bis-and tetrakis (carboxylic acid) …

Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The
conjugates include several cyanine dyes with a variety of bis-and tetrakis (carboxylic acid) …

Cyanine and Indocyanine dye compounds and bioconjugates are disclosed. The present
invention includes several cyanine and indocyanine dyes, including bioconjugates of the …

The traditional labeling method for targeted NIR fluorescence probes requires directly
covalent-bonded conjugation of targeting domains and fluorophores in vitro. Although this …

12. Will Compounds and methods a disclosed that are useful for 5. 5 69. 587. A 10/1996
Waggoner noninvasive imaging in the near-infrared (NIR) spectral 5. 57 1388 A 1 1/1996 …