3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration

D Kang, Z Liu, C Qian, J Huang, Y Zhou, X Mao, Q Qu… - Acta biomaterialia, 2023 - Elsevier
Hair follicle (HF) regeneration remains challenging, principally due to the absence of a
platform that can successfully generate the microenvironmental cues of hair neogenesis …

[HTML][HTML] Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering

Z Liu, J Huang, D Kang, Y Zhou, L Du, Q Qu, J Wang… - Acta Biomaterialia, 2023 - Elsevier
The restoration of hair-inductive potential in human dermal papilla cells (hDPCs) is a
tremendous challenge for hair regeneration. Much of the research thus far has indicated that …

[HTML][HTML] Preparation of hair beads and hair follicle germs for regenerative medicine

T Kageyama, L Yan, A Shimizu, S Maruo, J Fukuda - Biomaterials, 2019 - Elsevier
Hair regenerative medicine is a promising approach for hair loss, during which autologous
follicular stem cells are transplanted into regions of hair loss to regenerate hairs. Because …

Hair follicle germs containing vascular endothelial cells for hair regenerative medicine

T Kageyama, YS Chun, J Fukuda - Scientific Reports, 2021 - nature.com
Hair regenerative medicine has emerged as a promising approach for the treatment of
severe hair loss. Recent advances in three-dimensional tissue engineering, such as …

Tissue engineering of human hair follicles using a biomimetic developmental approach

HE Abaci, A Coffman, Y Doucet, J Chen… - Nature …, 2018 - nature.com
Human skin constructs (HSCs) have the potential to provide an effective therapy for patients
with significant skin injuries and to enable human-relevant drug screening for skin diseases; …

Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine

T Kageyama, C Yoshimura, D Myasnikova, K Kataoka… - Biomaterials, 2018 - Elsevier
Hair follicle morphogenesis is triggered by reciprocal interactions between hair follicle germ
(HFG) epithelial and mesenchymal layers. Here, we developed a method for large-scale …

3D multicellular micropatterning biomaterials for hair regeneration and vascularization

J Ma, C Qin, J Wu, H Zhuang, L Du, J Xu, C Wu - Materials Horizons, 2023 - pubs.rsc.org
Hair loss caused by the abnormal functions of hair follicles in skin can seriously impact the
quality of an individual's life. The development of sophisticated skin tissue-engineered …

3D printing of skin equivalents with hair follicle structures and epidermal‐papillary‐dermal layers using gelatin/hyaluronic acid hydrogels

MS Kang, M Kwon, SH Lee, WH Kim… - Chemistry–An Asian …, 2022 - Wiley Online Library
Recent advances in three‐dimensional (3D) bioprinting technologies have enabled the
fabrication of sophisticated live 3D tissue analogs. Despite the existing hydrogel‐based …

Establishment of an in vitro organoid model of dermal papilla of human hair follicle

AC Gupta, S Chawla, A Hegde, D Singh… - Journal of Cellular …, 2018 - Wiley Online Library
Human hair dermal papilla (DP) cells are specialized mesenchymal cells that play a pivotal
role in hair regeneration and hair cycle activation. The current study aimed to first develop …

Scalable and high-throughput production of an injectable platelet-rich plasma (PRP)/cell-laden microcarrier/hydrogel composite system for hair follicle tissue …

Y Zhang, P Yin, J Huang, L Yang, Z Liu, D Fu… - Journal of …, 2022 - Springer
Background Tissue engineering of hair follicles (HFs) has enormous potential for hair loss
treatment. However, certain challenges remain, including weakening of the dermal papilla …