[HTML][HTML] BarA/UvrY differentially regulates prodigiosin biosynthesis and swarming motility in Serratia marcescens FS14

X Liu, D Xu, D Wu, M Xu, Y Wang, W Wang… - Research in …, 2023 - Elsevier
BarA/UvrY, a two-component system and global regulator that controls expression of more
than a hundred of genes involved in virulence, motility, biofilm formation, and central carbon …

Regulator RcsB controls prodigiosin synthesis and various cellular processes in Serratia marcescens JNB5-1

X Pan, M Tang, J You, F Liu, C Sun… - Applied and …, 2021 - Am Soc Microbiol
Prodigiosin (PG), a red linear tripyrrole pigment normally secreted by Serratia marcescens,
has received attention for its reported immunosuppressive, antimicrobial, and anticancer …

Comparative transcriptome analysis reveals metabolic regulation of prodigiosin in Serratia marcescens

Y Sun, L Wang, T Osire, W Fu, G Yi, ST Yang… - Systems Microbiology …, 2021 - Springer
Prodigiosin is a secondary metabolite mainly produced at 30° C in Serratia marcescens, but
it can hardly be synthetized at 37° C or higher. In this study, we provide insight into the …

[HTML][HTML] PtrA regulates prodigiosin synthesis and biological functions in Serratia marcescens FZSF02

J Lin, Y Yu, K Zhao, J Zhao, C Rensing… - Frontiers in …, 2023 - frontiersin.org
Serratia marcescens is a gram-negative bacterium that is able to produce many secondary
metabolites, such as the prominent red pigment prodigiosin (PG). In this work, a ptrA …

LysR-Type Transcriptional Regulator MetR Controls Prodigiosin Production, Methionine Biosynthesis, Cell Motility, H2O2 Tolerance, Heat Tolerance, and …

X Pan, C Sun, M Tang, J You, T Osire… - Applied and …, 2020 - Am Soc Microbiol
Prodigiosin, a secondary metabolite produced by Serratia marcescens, has attracted
attention due to its immunosuppressive, antimicrobial, and anticancer properties. However …

[HTML][HTML] RpoS is a pleiotropic regulator of motility, biofilm formation, exoenzymes, siderophore and prodigiosin production, and trade-off during prolonged stationary …

H Qin, Y Liu, X Cao, J Jiang, W Lian, D Qiao, H Xu… - PLoS …, 2020 - journals.plos.org
Prodigiosin is an important secondary metabolite produced by Serratia marcescens. It can
help strains resist stresses from other microorganisms and environmental factors to achieve …

[HTML][HTML] Transcriptional factor OmpR positively regulates prodigiosin biosynthesis in Serratia marcescens FZSF02 by binding with the promoter of the prodigiosin …

X Jia, K Zhao, F Liu, J Lin, C Lin, J Chen - Frontiers in Microbiology, 2022 - frontiersin.org
Prodigiosin is a promising secondary metabolite mainly produced by Serratia marcescens.
The production of prodigiosin by S. marcescens is regulated by different kinds of regulatory …

[HTML][HTML] Improving prodigiosin production by transcription factor engineering and promoter engineering in Serratia marcescens

X Pan, J You, M Tang, X Zhang, M Xu, T Yang… - Frontiers in …, 2022 - frontiersin.org
Prodigiosin (PG), a red linear tripyrrole pigment produced by Serratia marcescens, has
attracted attention due to its immunosuppressive, antimicrobial, and anticancer properties …

Mechanisms underlying the inhibitory effects of Cd2+ on prodigiosin synthesis in Serratia marcescens KMR-3

G Zhu, W Tan, L Xie, C Ma, X Chen, S Zhang… - Journal of Inorganic …, 2022 - Elsevier
Abstract Prodigiosin (2-methyl-3-pentyl-6-methoxyprodiginine), a red-colored microbial
pigment, is produced in large quantities by Serratia marcescens KMR-3. This bacterium can …

[HTML][HTML] Identification of Essential Genes Associated With Prodigiosin Production in Serratia marcescens FZSF02

X Jia, F Liu, K Zhao, J Lin, Y Fang, S Cai, C Lin… - Frontiers in …, 2021 - frontiersin.org
Prodigiosin is a promising secondary metabolite produced mainly by Serratia strains. To
study the global regulatory mechanism of prodigiosin biosynthesis, a mutagenesis library …