[HTML][HTML] Atypical Membrane Topology and Heteromeric Function of Drosophila Odorant Receptors In Vivo

R Benton, S Sachse, SW Michnick, LB Vosshall - PLoS biology, 2006 - journals.plos.org
Drosophila olfactory sensory neurons (OSNs) each express two odorant receptors (ORs): a
divergent member of the OR family and the highly conserved, broadly expressed receptor …

Chemoreceptor co-expression in Drosophila melanogaster olfactory neurons

D Task, CC Lin, A Vulpe, A Afify, S Ballou, M Brbic… - Elife, 2022 - elifesciences.org
Drosophila melanogaster olfactory neurons have long been thought to express only one
chemosensory receptor gene family. There are two main olfactory receptor gene families in …

Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum

T Elmore, R Ignell, JR Carlson… - Journal of …, 2003 - Soc Neuroscience
In vertebrates, individual olfactory neurons are thought to express a single odorant receptor
(Or) gene, but it is not clear that all odor-evoked activity in each neuron is exclusively …

Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells

A Kiely, A Authier, AV Kralicek, CG Warr… - Journal of Neuroscience …, 2007 - Elsevier
Olfactory receptors (ORs) are seven transmembrane proteins that are responsible for the
transduction of volatiles into neuronal signals. Their low sequence homology means that the …

[HTML][HTML] Membrane topology of the Drosophila OR83b odorant receptor

C Lundin, L Käll, SA Kreher, K Kapp, EL Sonnhammer… - FEBS letters, 2007 - Elsevier
By analogy to mammals, odorant receptors (ORs) in insects, such as Drosophila
melanogaster, have long been thought to belong to the G-protein coupled receptor (GPCR) …

Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system

CH Wetzel, HJ Behrendt… - Proceedings of the …, 2001 - National Acad Sciences
Odorant receptors (ORs) constitute the molecular basis for the detection of volatile odorous
molecules and the perception of smell. Our understanding of chemical senses has been …

[HTML][HTML] Transmembrane segment 3 of Drosophila melanogaster odorant receptor subunit 85b contributes to ligand-receptor interactions

AS Nichols, CW Luetje - Journal of Biological Chemistry, 2010 - ASBMB
The OR class insect odorant receptors are ligand-gated ion channels comprised of at least
one common subunit (OR83b in Drosophila) and at least one putative odorant-binding …

[HTML][HTML] Genetic and functional subdivision of the Drosophila antennal lobe

E Fishilevich, LB Vosshall - Current Biology, 2005 - cell.com
Olfactory systems confer the recognition and discrimination of a large number of structurally
distinct odor molecules. Recent molecular analysis of odorant receptor (OR) genes and …

[HTML][HTML] Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction

MC Larsson, AI Domingos, WD Jones, ME Chiappe… - Neuron, 2004 - cell.com
Fruit flies are attracted by a diversity of odors that signal the presence of food, potential
mates, or attractive egg-laying sites. Most Drosophila olfactory neurons express two types of …

Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins

R Smart, A Kiely, M Beale, E Vargas, C Carraher… - Insect biochemistry and …, 2008 - Elsevier
Olfaction in Drosophila is mediated by a large family of membrane-bound odorant receptor
proteins (Ors). In heterologous cells, we investigated whether the structural features and …