The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

In this article, we briefly review the endocytic pathways used by cells, pointing out their
defining characteristics and highlighting physical limitations that may direct the …

Novel nanomaterials are being developed to improve diagnosis and therapy of diseases
through effective delivery of drugs, biopharmaceutical molecules and imaging agents to …

Endocytosis is a critical step in the process by which many therapeutic nanomedicines reach
their intracellular targets. Our understanding of cellular uptake mechanisms has developed …

Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

More than 40 nanomedicines are already in routine clinical use with a growing number
following in preclinical and clinical development. The therapeutic objectives are often …

Nanomaterials promise to improve disease diagnosis and treatment by enhancing the
delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In …

Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Using nanoparticles to deliver drugs to cells has the potential to revolutionize the treatment
of many diseases, including HIV, cancer, and diabetes. One of the major challenges facing …

Nanoparticles (NPs) are of similar size to typical cellular components and proteins, and can
efficiently intrude living cells. A detailed understanding of the involved processes at the …