Antibody response to a new member of the DBL family (EBP2) after a brief Plasmodium vivax exposure

BAS Lima, GM Fernandes, LM Torres… - PLOS Neglected …, 2022 - journals.plos.org
Plasmodium vivax blood-stage invasion into reticulocyte is critical for parasite development.
Thus, validation of novel parasite invasion ligands is essential for malaria vaccine …

[HTML][HTML] Natural genetic diversity of the DBL domain of a novel member of the Plasmodium vivax erythrocyte binding-like proteins (EBP2) in the Amazon rainforest

GM Fernandes, GH Rodrigues-Mattos… - Infection, Genetics and …, 2024 - Elsevier
In malaria parasites, the erythrocyte binding-like proteins (EBL) are a family of invasion
proteins that are attractive vaccine targets. In the case of Plasmodium vivax, the widespread …

[HTML][HTML] Naturally acquired antibodies to Plasmodium vivax Duffy binding protein (DBP) in rural Brazilian Amazon

FA Souza-Silva, M da Silva-Nunes… - The American journal …, 2010 - ncbi.nlm.nih.gov
Duffy binding protein (DBP), a leading malaria vaccine candidate, plays a critical role in
Plasmodium vivax erythrocyte invasion. Sixty-eight of 366 (18.6%) subjects had IgG anti …

Inhibitory Properties of the Antibody Response to Plasmodium vivax Duffy Binding Protein in an Area with Unstable Malaria Transmission

IP Ceravolo, FA Souza‐Silva… - Scandinavian …, 2008 - Wiley Online Library
The function of the Plasmodium vivax Duffy binding protein (DBP) during the erythrocyte
invasion process is critical for successful parasite growth and pathogenesis in human …

[PDF][PDF] Anti-Plasmodium vivax duffy binding protein antibodies measure exposure to malaria in the Brazilian Amazon

IP Ceravolo, O Bruña-Romero, EM Braga… - American Journal of …, 2005 - academia.edu
Plasmodium vivax Duffy binding protein (DBP) is functionally important in the erythrocyte
invasion process and provides a logical target for vaccine-mediated immunity. In the current …

Naturally acquired inhibitory antibodies to Plasmodium vivax Duffy binding protein are short-lived and allele-specific following a single malaria infection

IP Ceravolo, BAM Sanchez, TN Sousa… - Clinical & …, 2009 - academic.oup.com
The Duffy binding protein of Plasmodium vivax (DBP) is a critical adhesion ligand that
participates in merozoite invasion of human Duffy-positive erythrocytes. A small outbreak of …

Worldwide Genetic Variability of the Duffy Binding Protein: Insights into Plasmodium vivax Vaccine Development

T Nóbrega de Sousa, LH Carvalho, CF Alves de Brito - PLoS One, 2011 - journals.plos.org
The dependence of Plasmodium vivax on invasion mediated by Duffy binding protein (DBP)
makes this protein a prime candidate for development of a vaccine. However, the …

[HTML][HTML] Evaluation of the antigenicity of universal epitopes from PvDBPII in individuals exposed to Plasmodium vivax malaria

P Martinez, C Lopez, C Saravia, M Vanegas… - Microbes and …, 2010 - Elsevier
The Duffy-binding protein (PvDBP) mediates invasion of reticulocytes by the malaria
parasite Plasmodium vivax. PvDBP has been recognized as a good vaccine candidate due …

Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical …

WQ He, AR Shakri, R Bhardwaj… - PLoS neglected …, 2019 - journals.plos.org
Background The Plasmodium vivax Duffy Binding Protein (PvDBP) is a key target of
naturally acquired immunity. However, region II of PvDBP, which contains the receptor …

Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein and Clinical Immunity to Malaria in Rural Amazonians

VC Nicolete, S Frischmann, S Barbosa… - The Journal of …, 2016 - academic.oup.com
Background Antibodies to the cysteine-rich domain II of Plasmodium vivax Duffy binding
protein (PvDBP) can inhibit binding of this parasite ligand to its receptor on red blood cells …