Disparate roles for C. elegans DNA translocase paralogs RAD-54.L and RAD-54.B in meiotic prophase germ cells
K Yamaya, B Wang, N Memar, AS Odiba… - Nucleic Acids …, 2023 - academic.oup.com
RAD54 family DNA translocases partner with RAD51 recombinases to ensure stable
genome inheritance, exhibiting biochemical activities both in promoting recombinase …
genome inheritance, exhibiting biochemical activities both in promoting recombinase …
Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination
The vast majority of eukaryotes possess two DNA recombinases: Rad51, which is
ubiquitously expressed, and Dmc1, which is meiosis-specific. The evolutionary origins of this …
ubiquitously expressed, and Dmc1, which is meiosis-specific. The evolutionary origins of this …
[HTML][HTML] RAD51: Beyond the break
IE Wassing, F Esashi - Seminars in cell & developmental biology, 2021 - Elsevier
As the primary catalyst of homologous recombination (HR) in vertebrates, RAD51 has been
extensively studied in the context of repair of double-stranded DNA breaks (DSBs). With …
extensively studied in the context of repair of double-stranded DNA breaks (DSBs). With …
Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination
A Lorenz, A Mehats, F Osman… - Nucleic Acids …, 2014 - academic.oup.com
During meiosis programmed DNA double-strand breaks (DSBs) are repaired by
homologous recombination using the sister chromatid or the homologous chromosome …
homologous recombination using the sister chromatid or the homologous chromosome …
Role of RAD51C and XRCC3 in genetic recombination and DNA repair
In germ line cells, recombination is required for gene reassortment and proper chromosome
segregation at meiosis, whereas in somatic cells it provides an important mechanism for the …
segregation at meiosis, whereas in somatic cells it provides an important mechanism for the …
Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function
The RAD51 recombinase assembles as helical nucleoprotein filaments on single-stranded
DNA (ssDNA) and mediates invasion and strand exchange with homologous duplex DNA …
DNA (ssDNA) and mediates invasion and strand exchange with homologous duplex DNA …
Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases
Homologous recombination plays key roles in double-strand break repair, rescue, and
repair of stalled replication forks and meiosis. The broadly conserved Rad51/RecA family of …
repair of stalled replication forks and meiosis. The broadly conserved Rad51/RecA family of …
Interaction with Rad51 is indispensable for recombination mediator function of Rad52
L Krejci, B Song, W Bussen, R Rothstein… - Journal of Biological …, 2002 - ASBMB
In the yeast Saccharomyces cerevisiae, the RAD52 gene is indispensable for homologous
recombination and DNA repair. Rad52 protein binds DNA, anneals complementary ssDNA …
recombination and DNA repair. Rad52 protein binds DNA, anneals complementary ssDNA …
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis
J Wesoly, S Agarwal, S Sigurdsson… - … and cellular biology, 2006 - Am Soc Microbiol
Homologous recombination is a versatile DNA damage repair pathway requiring Rad51 and
Rad54. Here we show that a mammalian Rad54 paralog, Rad54B, displays physical and …
Rad54. Here we show that a mammalian Rad54 paralog, Rad54B, displays physical and …