Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma

H Zhai, S Zhong, R Wu, Z Mo, S Zheng, J Xue… - Epigenetics, 2023 - Taylor & Francis
Ferroptosis is a newly characterized form of iron-dependent non-apoptotic cell death, which
is closely associated with cancer progression. However, the functions and mechanisms in …

[HTML][HTML] Ferroptosis is involved in the progression of hepatocellular carcinoma through the circ0097009/miR-1261/SLC7A11 axis

N Lyu, Y Zeng, Y Kong, Q Chen, H Deng… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Circular RNAs (circRNAs) are a class of non-coding RNAs that have been
demonstrated to play important roles in tumorigenesis. However, how circRNAs regulate the …

CircIL4R facilitates the tumorigenesis and inhibits ferroptosis in hepatocellular carcinoma by regulating the miR‐541‐3p/GPX4 axis

Q Xu, L Zhou, G Yang, F Meng, Y Wan… - Cell biology …, 2020 - Wiley Online Library
Ferroptosis is a specific iron‐dependent cell death form that can induce the production of
lipid peroxide, but the roles of circular RNAs (circRNAs) in ferroptosis are completely …

WTAP-mediated m6A modification on circCMTM3 inhibits hepatocellular carcinoma ferroptosis by recruiting IGF2BP1 to increase PARK7 stability

S Chen, H Xia, L Sheng - Digestive and Liver Disease, 2023 - Elsevier
Background Hepatocellular carcinoma (HCC) has poor prognosis and high mortality.
CircCMTM3 was significantly up-regulated in HCC. However, the mechanism of circCMTM3 …

[HTML][HTML] RBMS1 regulates lung cancer ferroptosis through translational control of SLC7A11

W Zhang, Y Sun, L Bai, L Zhi, Y Yang… - The Journal of …, 2021 - Am Soc Clin Investig
Ferroptosis, an iron-dependent nonapoptotic cell death, is a highly regulated tumor
suppressing process. However, functions and mechanisms of RNA-binding proteins in …

MiR‐15a‐3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer

L Liu, H Yao, X Zhou, J Chen, G Chen… - Molecular …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cancer‐related deaths throughout the
world. Ferroptosis is a recently regulated form of cell death, lately gains attention. MicroRNA …

miR‐21‐5p inhibits ferroptosis in hepatocellular carcinoma cells by regulating the AKT/mTOR signaling pathway through MELK

Z Hu, L Li, M Li, X Zhang, Y Zhang… - Journal of Immunology …, 2023 - Wiley Online Library
Background. Hepatocellular carcinoma (HCC) is one of the most prevalent cancers, and its
incidence rate is increasing worldwide. At present, there is no ideal treatment for HCC. In …

MicroRNA‐214‐3p enhances erastin‐induced ferroptosis by targeting ATF4 in hepatoma cells

T Bai, R Liang, R Zhu, W Wang… - Journal of cellular …, 2020 - Wiley Online Library
Primary liver cancer is the second most frequent cause of cancer‐related deaths.
Ferroptosis, a recognized form of regulated cell death, recently gains attention. MicroRNA …

[HTML][HTML] CircP4HB regulates ferroptosis via SLC7A11-mediated glutathione synthesis in lung adenocarcinoma

CF Pan, K Wei, ZJ Ma, YZ He, JJ Huang… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background Circular ribonucleic acids (circRNAs) play a key role in the development of
different types of cancer. Ferroptosis is a type of programmed cell death that contributes to …

[HTML][HTML] CircRNF10 triggers a positive feedback loop to facilitate progression of glioblastoma via redeploying the ferroptosis defense in GSCs

C Wang, M Zhang, Y Liu, D Cui, L Gao… - Journal of Experimental & …, 2023 - Springer
Background Glioma exhibit heterogeneous susceptibility for targeted ferroptosis. How
circRNAs alterations in glioma promote iron metabolism and ferroptosis defense remains …