Introduction Aging skeletal muscle is associated with not only a reduction in muscle size and
strength but also in muscle quality which reflects an increase in fatty infiltration of muscle. In …

Prostate cancer (PCa) is the most common visceral malignancy in men with androgen
deprivation therapy (ADT) the preferred therapy to suppress testosterone production and …

Androgen deprivation therapy (ADT) for prostate cancer (PCa) can compromise muscle
health. Hence, we aimed to quantify the prevalence of sarcopenia (ie, compromised lean …

This study examined the effects of androgen suppression therapy (AST) on upper and lower
body muscle strength and a range of direct measures of physical performance using a cross …

Androgen deprivation therapy (ADT) improves life expectancy in prostate cancer (PCa)
patients, but is associated with adverse effects on muscle mass. Here, we investigated the …

The changes in body composition are early adverse effects of androgen deprivation therapy
(ADT); however, their prognostic impact remains unclear in prostate cancer. This study …

Purpose Androgen suppression therapy (AST) results in musculoskeletal toxicity that
reduces physical function and quality of life. This study examined the impact of a combined …

Objective Androgen deprivation therapy alters body composition promoting a significant loss
in skeletal muscle (SM) mass through inflammation and oxidative damage. We verified …

Androgen deprivation therapy (ADT) decreases muscle mass and function but no human
studies have investigated the underlying genetic or cellular effects. We tested the hypothesis …

Background Studies indicate that strength training has beneficial effects on clinical health
outcomes in prostate cancer patients during androgen deprivation therapy. However …