[HTML][HTML] Proteomic discovery of prognostic protein biomarkers for persisting problems after mild traumatic brain injury

MY Lee, M Son, HH Lee, MG Kang, SJ Yun, HG Seo… - Scientific Reports, 2023 - nature.com
Some individuals with mild traumatic brain injury (mTBI), also known as concussion, have
neuropsychiatric and physical problems that last longer than a few months. Symptoms …

[HTML][HTML] Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic …

A Morin, R Davis, T Darcey, M Mullan, B Mouzon… - Molecular Brain, 2022 - Springer
Repetitive mild traumatic brain injury (r-mTBI) is the most widespread type of brain trauma
worldwide. The cumulative injury effect triggers long-lasting pathological and molecular …

Characteristics of patients included and enrolled in studies on the prognostic value of serum biomarkers for prediction of postconcussion symptoms following a mild …

E Mercier, PA Tardif, M Emond, MC Ouellet… - BMJ open, 2017 - bmjopen.bmj.com
Objective Mild traumatic brain injury (mTBI) has been insufficiently researched, and its
definition remains elusive. Investigators are confronted by heterogeneity in patients …

[HTML][HTML] Current state and prospects of development of blood-based biomarkers for mild traumatic brain injury

HH Lee, WH Lee, HG Seo, D Han, Y Kim… - Brain & …, 2017 - e-bnr.org
The current understanding of the pathophysiology of mild traumatic brain injury (mTBI) is,
without doubt, incomplete. Nevertheless, we tried to summarize the state-of-the-art …

[HTML][HTML] Multivariate analysis of traumatic brain injury: development of an assessment score

JE Buonora, AM Yarnell, RC Lazarus… - Frontiers in …, 2015 - frontiersin.org
Important challenges for the diagnosis and monitoring of mild traumatic brain injury (mTBI)
include the development of plasma biomarkers for assessing neurologic injury, monitoring …

[HTML][HTML] A review of molecular and genetic factors for determining mild traumatic brain injury severity and recovery

M Tajik, MD Noseworthy - Brain Disorders, 2022 - Elsevier
Mild traumatic brain injuries (mTBI) affect millions of people globally every year. The clinical
presentation of this injury is highly variable, and its progression from the acute to chronic …

Expressive proteomics profile changes of injured human brain cortex due to acute brain trauma

X Yang, S Yang, J Wang, X Zhang, C Wang, G Hong - Brain Injury, 2009 - Taylor & Francis
Objective: To find the expressive proteomics changes in damaged human brain cortex after
traumatic brain injury (TBI). Method: By rapid high-throughput and precise proteomic …

Blood biomarkers for assessment of mild traumatic brain injury and chronic traumatic encephalopathy

MI Hiskens, AG Schneiders, M Angoa-Pérez… - Biomarkers, 2020 - Taylor & Francis
Mild traumatic brain injuries (mTBI) are prevalent and can result in significant debilitation.
Current diagnostic methods have implicit limitations, with clinical assessment tools reliant on …

Research on the potential biomarkers of mild traumatic brain injury: a systematic review and bibliometric analysis

Y Liu, C Wang, Z Pi, T Wang, C Zhang, J Cai - Molecular neurobiology, 2023 - Springer
Reliable diagnostic methods for mild traumatic brain injury (mTBI) are lacking, and many
researchers continue to search for objective biomarkers that can both define and detect …

[HTML][HTML] Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with …

GJB Clarke, T Follestad, T Skandsen… - Journal of …, 2024 - Springer
Background Identifying individuals with intracranial injuries following mild traumatic brain
injury (mTBI), ie complicated mTBI cases, is important for follow-up and prognostication. The …