A new era of medical technology in cancer treatment is a directly specific modification of
gene expression in tumor cells by nucleic acid delivery. Currently, the main challenge to …

Non‐viral gene delivery has emerged as a promising approach for therapy in cancer
treatment. Polyethylenimine (PEI) is a prominent transfecting agent, but due to toxicity and …

Polyethyleneimine (PEI) is a cationic polymer used as a gold standard in non-viral gene
delivery. The extraordinary cationic charge and buffering capacity of the PEI has been …

Introduction: Branched and linear polyethylenimines (PEIs) are cationic polymers that have
been used to deliver nucleic acids both in vitro and in vivo. Owing to the high cationic …

The polycation polyethylenimine (PEI) has recently been widely employed for the design of
DNA delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

The development of gene delivery vectors with high efficiency and biocompatibility is one of
the key points of gene therapy. A series of polycations were prepared from polyethylenimine …

Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

Gene therapy has become a promising strategy for the treatment of genetically based
diseases, such as cancer, which are currently considered incurable. A major obstacle in the …

The meaning of gene therapy is the delivery of DNA or RNA to cells for the treatment or
prevention of genetic disorders. The success rate of gene therapy depends on the …

The major aim of nonviral delivery systems for gene therapy is to mediate high levels of
gene expression with low toxicity. Nowadays, one of the most successful synthetic …