APRi predicts native liver survival by reflecting portal fibrogenesis and hepatic neovascularization at the time of portoenterostomy in biliary atresia

JS Suominen, H Lampela, P Heikkilä, J Lohi… - Journal of Pediatric …, 2015 - Elsevier
Background Aspartate aminotransferase-to-platelet ratio index (APRi) may be useful
noninvasive prognostic tool in biliary atresia (BA). We studied whether APRi predicts native …

Aspartate aminotransferase-to-platelet ratio index (APRi) in infants with biliary atresia: prognostic value at presentation

A Grieve, E Makin, M Davenport - Journal of pediatric surgery, 2013 - Elsevier
BACKGROUND: Biliary atresia (BA) is a progressive obliterative cholangiopathy leading to
liver fibrosis and cirrhosis. The aspartate aminotransferase-to-platelet ratio index (APRi) has …

The AST-to-platelet ratio index (APRi) at kasai portoenterostomy: standing the test of time

A Muntean, R Kronfli, E Makin, M Davenport - Journal of Pediatric Surgery, 2023 - Elsevier
Aims The outcomes following surgical treatment of infants with biliary atresia (BA) varies
across the world with many possible confounding factors. APRi (AST-to-platelet ratio index) …

Assessment of liver fibrosis and cirrhosis by aspartate aminotransferase-to-platelet ratio index in children with biliary atresia

SY Kim, JY Seok, SJ Han, H Koh - Journal of pediatric …, 2010 - journals.lww.com
Background: In patients with biliary atresia (BA), liver fibrosis and cirrhosis commonly occur
even after Kasai hepatoportoenterostomy. Although liver biopsy is the gold standard to …

[HTML][HTML] Validation of aspartate aminotransferase to platelet ratio for diagnosis of liver fibrosis and prediction of postoperative prognosis in infants with biliary atresia

LY Yang, J Fu, XF Peng, SY Pang, KK Gao… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To validate the value of aspartate aminotransferase to platelet ratio index (APRI) in
assessment of liver fibrosis and prediction of postoperative prognosis of biliary atresia (BA) …

Aspartate transaminase-to-platelet ratio index is not correlated with severity of fibrosis or survival in children with biliary atresia

RC Lind, HJ Verkade, RJ Porte… - Journal of pediatric …, 2012 - journals.lww.com
Kim et al (1) postulating that the aspartate transaminaseto-platelet ratio index (APRI) can be
used as a noninvasive, easily available surrogate marker for the severity of liver fibrosis in …

Outcome after portoenterostomy in biliary atresia: pivotal role of degree of liver fibrosis and intensity of stellate cell activation

E Shteyer, GA Ramm, C Xu, FV White… - Journal of pediatric …, 2006 - journals.lww.com
Objectives: Biliary atresia (BA), a congenital idiopathic obliterative cholangiopathy, rapidly
leads to liver cirrhosis and liver failure if untreated. A timely Kasai portoenterostomy (KP) …

Correlation between gamma-glutamyl transpeptidase activity and outcomes after Kasai portoenterostomy for biliary atresia

K Ihn, IG Ho, EY Chang, SJ Han - Journal of Pediatric Surgery, 2018 - Elsevier
Background/purpose The role of serum gamma-glutamyl transpeptidase (GGT) levels in
predicting clinical outcomes after Kasai portoenterostomy (KPE) is unknown. This study …

Comprehensive assessment of prognosis after laparoscopic portoenterostomy for biliary atresia

H Nakamura, H Koga, J Cazares, T Okazaki… - Pediatric surgery …, 2016 - Springer
Purpose Total bilirubin (T-bil) is used universally for monitoring post-portoenterostomy (PE)
biliary atresia (BA) patients although other biochemical markers [BM; AST/ALT and platelet …

Bilirubin level 1 week after hepatoportoenterostomy predicts native liver survival in biliary atresia

CY Huang, MH Chang, HL Chen, YH Ni, HY Hsu… - Pediatric …, 2020 - nature.com
Background To determine a very early predictive biomarker after hepatoportoenterostomy
(HPE) for the prediction of native liver survival in biliary atresia (BA) patients. Methods A …