One Health or Three? Transmission modelling of Klebsiella isolates reveals ecological barriers to transmission between humans, animals and the environment

H Thorpe, R Booton, T Kallonen, MJ Gibbon, N Couto… - BioRxiv, 2021 - biorxiv.org
The Klebsiella group is highly diverse both genetically and ecologically, being commonly
recovered from humans, livestock, plants, soil, water, and wild animals. Many species are …

[HTML][HTML] A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings

HA Thorpe, R Booton, T Kallonen, MJ Gibbon… - Nature …, 2022 - nature.com
The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is
genetically and ecologically diverse. Many species are opportunistic pathogens and can …

[HTML][HTML] Phenotypic and Genetic Characterization of Klebsiella pneumoniae Isolates from Wild Animals in Central Italy

A Chiaverini, A Cornacchia, G Centorotola, EE Tieri… - Animals, 2022 - mdpi.com
Simple Summary Klebsiella pneumoniae is an opportunistic bacterium known as a
nosocomial pathogen, but it is able to colonize a multitude of ecological niches, both free …

Limited transmission of Klebsiella pneumoniae among humans, animals, and the environment in a Caribbean Island, Guadeloupe (French West Indies)

A Dereeper, G Gruel, M Pot, D Couvin… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT Guadeloupe (French West Indies), a Caribbean island, is an ideal place to study
the reservoirs of the Klebsiella pneumoniae species complex (KpSC) and identify the routes …

[HTML][HTML] Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level

VN Kachalov, H Nguyen, S Balakrishna… - PLoS computational …, 2021 - journals.plos.org
Beta-lactam-and in particular carbapenem-resistant Enterobacteriaceae represent a major
public health threat. Despite strong variation of resistance across geographical settings …

Genomic epidemiology of Klebsiella pneumoniae in Italy and novel insights into the origin and global evolution of its resistance to carbapenem antibiotics

S Gaiarsa, F Comandatore, P Gaibani… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Klebsiella pneumoniae is at the forefront of antimicrobial resistance for Gram-negative
pathogenic bacteria, as strains resistant to third-generation cephalosporins and …

A One Health Study of the Genetic Relatedness of Klebsiella pneumoniae and Their Mobile Elements in the East of England

C Ludden, D Moradigaravand… - Clinical Infectious …, 2020 - academic.oup.com
Background Klebsiella pneumoniae is a human, animal, and environmental commensal and
a leading cause of nosocomial infections, which are often caused by multiresistant strains …

[HTML][HTML] Genome-Based Analysis of Klebsiella spp. Isolates from Animals and Food Products in Germany, 2013–2017

K Klaper, JA Hammerl, J Rau, Y Pfeifer, G Werner - Pathogens, 2021 - mdpi.com
The increase in infections with multidrug-resistant and virulent Klebsiella pneumoniae (K.
pneumoniae) strains poses a serious threat to public health. However, environmental …

Whole-genome sequencing to identify drivers of carbapenem-resistant Klebsiella pneumoniae transmission within and between regional long-term acute-care …

JH Han, Z Lapp, F Bushman… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an antibiotic resistance threat of
the highest priority. Given the limited treatment options for this multidrug-resistant organism …

[HTML][HTML] Diversity in the Characteristics of Klebsiella pneumoniae ST101 of Human, Environmental, and Animal Origin

S De Koster, JP Rodriguez Ruiz, SG Rajakani… - Frontiers in …, 2022 - frontiersin.org
Background Klebsiella pneumoniae ST101 is an emerging high-risk clone which exhibits
extensive drug resistance. Bacterial strains residing in multiple hosts show unique …