[HTML][HTML] Dyspnea in COPD: new mechanistic insights and management implications
Dyspnea is the most common symptom experienced by patients with chronic obstructive
pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary …
pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary …
Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable
DE O'Donnell, RB Banzett… - Proceedings of the …, 2007 - atsjournals.org
Effective management of dyspnea in chronic obstructive pulmonary disease (COPD)
requires a clearer understanding of its underlying mechanisms. This roundtable reviews …
requires a clearer understanding of its underlying mechanisms. This roundtable reviews …
Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions
NA Hanania, DE O'Donnell - International journal of chronic …, 2019 - Taylor & Francis
Dyspnea is a distressing, debilitating, and near-ubiquitous symptom affecting patients with
COPD. In addition to the functional consequences of dyspnea, which include activity …
COPD. In addition to the functional consequences of dyspnea, which include activity …
Pathophysiology of dyspnea in COPD
A Anzueto, M Miravitlles - Postgraduate medicine, 2017 - Taylor & Francis
Dyspnea refers to the sensation of breathlessness, shortness of breath, or difficulty breathing
that is commonly observed in patients with respiratory and cardiac disease. In the United …
that is commonly observed in patients with respiratory and cardiac disease. In the United …
[HTML][HTML] Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing
DE O'Donnell, AF Elbehairy, A Faisal… - European …, 2016 - Eur Respiratory Soc
Activity-related dyspnoea is often the most distressing symptom experienced by patients with
chronic obstructive pulmonary disease (COPD) and can persist despite comprehensive …
chronic obstructive pulmonary disease (COPD) and can persist despite comprehensive …
Therapeutic implications of the pathophysiology of COPD
PT Macklem - European Respiratory Journal, 2010 - Eur Respiratory Soc
This review examines 18 studies published≥ 30 yrs ago. They show that the earliest
manifestation of chronic obstructive pulmonary disease (COPD) is an increase in residual …
manifestation of chronic obstructive pulmonary disease (COPD) is an increase in residual …
Exercise training improves exertional dyspnea in patients with COPD: evidence of the role of mechanical factors
F Gigliotti, C Coli, R Bianchi, I Romagnoli, B Lanini… - Chest, 2003 - Elsevier
Background To our knowledge, no data have been reported on the effects of exercise
training (EXT) on central respiratory motor output or neuromuscular coupling (NMC) of the …
training (EXT) on central respiratory motor output or neuromuscular coupling (NMC) of the …
The pathophysiology of dyspnea and exercise intolerance in chronic obstructive pulmonary disease
DE O'Donnell, MD James, KM Milne… - Clinics in chest …, 2019 - chestmed.theclinics.com
In the last American Thoracic Society (ATS) statement, dyspnea was defined as “a subjective
experience of breathing discomfort that consists of qualitatively distinct sensations that vary …
experience of breathing discomfort that consists of qualitatively distinct sensations that vary …
[HTML][HTML] Lung hyperinflation in COPD: applying physiology to clinical practice
DE O'Donnell, KA Webb, JA Neder - COPD Research and Practice, 2015 - Springer
In chronic obstructive pulmonary disease (COPD), worsening expiratory flow limitation
together with alteration in the elastic properties of the lung are associated with progressive …
together with alteration in the elastic properties of the lung are associated with progressive …
Mechanisms of activity-related dyspnea in pulmonary diseases
DE O'Donnell, J Ora, KA Webb, P Laveneziana… - Respiratory physiology …, 2009 - Elsevier
Progressive activity-related dyspnea dominates the clinical presentation of patients afflicted
by chronic obstructive and restrictive lung diseases. This symptom invariably leads to activity …
by chronic obstructive and restrictive lung diseases. This symptom invariably leads to activity …