Alzheimer's disease (AD) is the most common form of dementia affecting elderly people. AD
is a multifaceted pathology characterized by accumulation of extracellular neuritic plaques …

Type 2 diabetes is a risk factor for developing Alzheimer's disease (AD). The underlying
mechanism that links up the two conditions seems to be the de-sensitization of insulin …

Hyperinsulinemia as well as type II diabetes mellitus are among the risk factors for
Alzheimer's disease (AD). However, the molecular and cellular basis that link insulin …

Alterations of the insulin signaling cascade underlie cognitive decline and the development
of several neurodegenerative diseases. In recent years, a great interest has been put in …

Alzheimer's disease (AD) and diabetes are currently considered among the top threats to
human health worldwide. Intriguingly, a connection between these diseases has been …

Compelling preclinical and clinical evidence supports a pathophysiological connection
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and …

Alzheimer's disease (AD) is the main type of dementia and is a disease with a profound
socioeconomic burden due to the lack of effective treatment. In addition to genetics and …

Introduction• Insulin, IGF‐1 in the brain• Glucose metabolism and AD• The insulin and IGF‐1
system in AD• The insulin and oxidative stress in AD• The insulin and IGF‐1R system and τ …

Individuals with type 2 diabetes have an increased risk for developing Alzheimer's disease
(AD), although the causal relationship remains poorly understood. Alterations in insulin …

Alzheimer disease (AD) is a chronic neurodegenerative disease that accounts for 60–70%
of dementia and is the sixth leading cause of death in the United States. The pathogenesis …