The effects of disease activity, inflammation, depression and cognitive fatigue on resting state fMRI in systemic lupus erythematosus

M Barraclough, S McKie, B Parker, R Elliott… - …, 2022 - academic.oup.com
Objectives Cognitive dysfunction (CD) and depression are interlinked comorbidities of SLE.
They may be the result of altered brain mechanisms. This study aimed to examine SLE …

Systemic lupus erythematosus-related brain abnormalities in the default mode network and the limbic system: A resting-state fMRI meta-analysis

L Wang, K Han, Q Huang, W Hu, J Mo, J Wang… - Journal of Affective …, 2024 - Elsevier
Background Systemic lupus erythematosus (SLE) is an immune-mediated and multi-
systemic disease which may affect the nervous system, causing neuropsychiatric SLE …

Resting state network functional connectivity abnormalities in systemic lupus erythematosus: correlations with neuropsychiatric impairment

R Bonacchi, MA Rocca, GA Ramirez, EP Bozzolo… - Molecular …, 2021 - nature.com
Neuropsychiatric manifestations are highly prevalent in systemic lupus erythematosus (SLE)-
patients. We aimed to unravel the substrates of these manifestations by investigating …

The effects of disease activity on neuronal and behavioural cognitive processes in systemic lupus erythematosus

M Barraclough, S McKie, B Parker, R Elliott… - …, 2022 - academic.oup.com
Objectives Factors common across many chronic diseases, such as fatigue and depression
affect cognitive dysfunction (CD) but the effect of SLE disease activity on CD remains …

Altered functional neuronal activity in neuropsychiatric lupus: a systematic review of the fMRI investigations

JA Mikdashi - Seminars in Arthritis and Rheumatism, 2016 - Elsevier
Objective Recent years have seen a rapid increase in the investigation of neuropsychiatric
lupus (NPSLE) through the use of functional magnetic resonance imaging (fMRI). Measuring …

Functional connectivity changes in core resting state networks are associated with cognitive performance in systemic lupus erythematosus

J Nystedt, P Mannfolk, A Jönsen… - Journal of …, 2019 - Wiley Online Library
To investigate core resting state networks in SLE patients with and without neuropsychiatric
symptoms by examining functional connectivity changes correlating with results of cognitive …

Symptoms of fatigue and depression is reflected in altered default mode network connectivity in multiple sclerosis

EA Høgestøl, GO Nygaard, D Alnæs, MK Beyer… - PLoS …, 2019 - journals.plos.org
Background Fatigue and depression are frequent and often co-occurring symptoms in
multiple sclerosis (MS). Resting-state functional magnetic resonance imaging (rs-fMRI) …

Abnormalities of frontal-parietal resting-state functional connectivity are related to disease activity in patients with systemic lupus erythematosus

J Hou, Y Lin, W Zhang, L Song, W Wu, J Wang, D Zhou… - PloS one, 2013 - journals.plos.org
Cerebral involvement is common in patients with systemic Lupus erythematosus (SLE) and
is characterized by multiple clinical presentations, including cognitive disorders, headaches …

Anxiety and depression severity in neuropsychiatric SLE are associated with perfusion and functional connectivity changes of the frontolimbic neural circuit: a resting …

D Antypa, NJ Simos, E Kavroulakis… - Lupus science & …, 2021 - lupus.bmj.com
Objective To examine the hypothesis that perfusion and functional connectivity disturbances
in brain areas implicated in emotional processing are linked to emotion-related symptoms in …

Altered cognitive function in systemic lupus erythematosus and associations with inflammation and functional and structural brain changes

M Barraclough, S McKie, B Parker, A Jackson… - Annals of the …, 2019 - ard.bmj.com
Objectives Cognitive dysfunction (CD) is common in systemic lupus erythematosus (SLE)
but the cause remains unclear and treatment options are limited. We aimed to compare …