Biodegradable PLGA85/15 nanoparticles as a delivery vehicle for Chlamydia trachomatis recombinant MOMP-187 peptide
MA Taha, SR Singh, VA Dennis - Nanotechnology, 2012 - iopscience.iop.org
Abstract Development of a Chlamydia trachomatis vaccine has been a formidable task partly
because of an ineffective delivery system. Our laboratory has generated a recombinant …
because of an ineffective delivery system. Our laboratory has generated a recombinant …
Chlamydia trachomatis recombinant MOMP encapsulated in PLGA nanoparticles triggers primarily T helper 1 cellular and antibody immune responses in mice: a …
SJ Fairley, SR Singh, AN Yilma, AB Waffo… - International journal …, 2013 - Taylor & Francis
We recently demonstrated by in vitro experiments that PLGA (poly D, L-lactide-co-glycolide)
potentiates T helper 1 (Th1) immune responses induced by a peptide derived from the …
potentiates T helper 1 (Th1) immune responses induced by a peptide derived from the …
Encapsulation of Recombinant MOMP in Extended-Releasing PLGA 85:15 Nanoparticles Confer Protective Immunity Against a Chlamydia muridarum Genital …
Recently we reported the immune-potentiating capacity of a Chlamydia nanovaccine (PLGA-
rMOMP) comprising rMOMP (recombinant major outer membrane protein) encapsulated in …
rMOMP) comprising rMOMP (recombinant major outer membrane protein) encapsulated in …
Formulation, characterization, and expression of a recombinant MOMP Chlamydia trachomatis DNA vaccine encapsulated in chitosan nanoparticles
CD Cambridge, SR Singh, AB Waffo… - International journal …, 2013 - Taylor & Francis
Chlamydia trachomatis is a bacterial sexually transmitted infection affecting millions of
people worldwide. Previous vaccination attempts have employed the recombinant major …
people worldwide. Previous vaccination attempts have employed the recombinant major …
Poly (lactic acid)–poly (ethylene glycol) nanoparticles provide sustained delivery of a Chlamydia trachomatis recombinant MOMP peptide and potentiate systemic …
PLA–PEG [poly (lactic acid)–poly (ethylene glycol)], a biodegradable copolymer, is
underexploited for vaccine delivery although it exhibits enhanced biocompatibility and slow …
underexploited for vaccine delivery although it exhibits enhanced biocompatibility and slow …
A nanovaccine formulation of Chlamydia recombinant MOMP encapsulated in PLGA 85: 15 nanoparticles augments CD4+ effector (CD44high CD62Llow) and …
Vaccine developmental strategies are utilizing antigens encapsulated in biodegradable
polymeric nanoparticles. Here, we developed a Chlamydia nanovaccine (PLGA-rMOMP) by …
polymeric nanoparticles. Here, we developed a Chlamydia nanovaccine (PLGA-rMOMP) by …
The Chlamydia M278 Major Outer Membrane Peptide Encapsulated in the Poly(lactic acid)-Poly(ethylene glycol) Nanoparticulate Self-Adjuvanting Delivery System Protects …
Recently, we reported that our PPM chlamydial nanovaccine [a biodegradable co-polymeric
PLA-PEG (poly (lactic acid)-poly (ethylene glycol))-encapsulated M278 peptide (derived …
PLA-PEG (poly (lactic acid)-poly (ethylene glycol))-encapsulated M278 peptide (derived …
Caveolin-mediated endocytosis of the Chlamydia M278 outer membrane peptide encapsulated in poly (lactic acid)-Poly (ethylene glycol) nanoparticles by mouse …
We previously developed a Chlamydia trachomatis nanovaccine (PPM) by encapsulating a
chlamydial M278 peptide within poly (lactic acid)-poly (ethylene glycol) biodegradable …
chlamydial M278 peptide within poly (lactic acid)-poly (ethylene glycol) biodegradable …
Future of human Chlamydia vaccine: potential of self-adjuvanting biodegradable nanoparticles as safe vaccine delivery vehicles
Introduction: There is a persisting global burden and considerable public health challenge
by the plethora of ocular, genital and respiratory diseases caused by members of the Gram …
by the plethora of ocular, genital and respiratory diseases caused by members of the Gram …
Chlamydia trachomatis: quest for an eye-opening vaccine breakthrough
Introduction Chlamydia trachomatis, commonly referred to as chlamydia (a bacterium), is a
common sexually transmitted infection, and if attended to early, it can be treatable. However …
common sexually transmitted infection, and if attended to early, it can be treatable. However …