The efficacy and safety of Apatinib in the treatment of advanced non-small cell lung cancer: A retrospective trial

J Wang, D Huang, W Yang, Q Song, Y Jia… - Frontiers in …, 2022 - frontiersin.org
Background As a potent inhibitor of the vascular endothelial growth factor (VEGF) signaling
pathway, Apatinib has been used in antitumor treatment for some time. The study aimed to …

[PDF][PDF] Apatinib in the treatment of advanced non-small-cell lung cancer: A meta-analysis

GC Yu, J Yang, B Ye, LL Xu, XY Li, GR Zheng - Math Biosci Eng, 2019 - aimspress.com
Objectives: The purpose of this meta-analysis was to evaluate the efficacy and toxicity profile
of apatinib for the treatment of advanced non-small cell lung cancer (NSCLC). Methods: We …

Apatinib for advanced nonsmall-cell lung cancer: a retrospective case series analysis

C Yang, W Feng, D Wu - Journal of Cancer Research and …, 2018 - journals.lww.com
Objectives: Apatinib, a tyrosine kinase inhibitor which selectively inhibits vascular
endothelial growth factor receptor-2, has been shown to be beneficial to patients with a …

A phase II, multicenter, placebo-controlled trial of apatinib in patients with advanced nonsquamous non-small cell lung cancer (NSCLC) after two previous treatment …

L Zhang, M Shi, C Huang, X Liu, J Xiong, G Chen… - 2012 - ascopubs.org
7548 Background: Apatinib is an oral, small molecular tyrosine-kinase inhibitor (TKI)
targeting vascular endothelial growth factor receptor (VEGFR). Phase II study has showed …

A Phase II Clinical Trial of Apatinib in Pretreated Advanced Non-Squamous Non–Small-Cell Lung Cancer

F Wu, S Zhang, A Xiong, G Gao, W Li, W Cai, C Su… - Clinical Lung Cancer, 2018 - Elsevier
Objectives Apatinib exhibits broad-spectrum antitumor activities by selectively inhibiting
vascular endothelial growth factor receptor-2. This study evaluated the efficacy and safety of …

Apatinib monotherapy for advanced non‐small cell lung cancer after the failure of chemotherapy or other targeted therapy

Z Liu, W Ou, N Li, SY Wang - Thoracic Cancer, 2018 - Wiley Online Library
Background Apatinib, a small‐molecule inhibitor of vascular endothelial growth factor
receptor 2 (VEGFR‐2), has proven to be effective and safe for treating patients with …

Efficacy and safety of apatinib in patients with advanced nonsmall cell lung cancer that failed prior chemotherapy or EGFR-TKIs: a pooled analysis

JT Ma, J Sun, L Sun, SL Zhang, LT Huang, CB Han - Medicine, 2018 - journals.lww.com
Background: Apatinib is a tyrosine kinase inhibitor (TKI) that selectively inhibits the vascular
endothelial growth factor receptor-2. A weighted pooled analysis was performed to evaluate …

[HTML][HTML] Apatinib for heavily treated patients with non-small cell lung cancer: Report of a case series and literature review

D Yang, R Dai, Q Zhang, P Fang - Saudi Journal of Biological Sciences, 2018 - Elsevier
Although many strategies have been developed for non-small cell lung cancer (NSCLC),
more secondary and further treatments are needed due to drug resistance or tumor …

Clinical investigation of the efficacy and toxicity of apatinib (YN968D1) in stage III/IV non‐small cell lung cancer after second‐line chemotherapy treatment: a …

D Zhang, C Zhang, J Huang, Y Guan, Q Guo - Thoracic cancer, 2018 - Wiley Online Library
Background This study was designed to assess the clinical efficacy and toxicity of apatinib
(YN968D1) as third or subsequent‐line treatment for stage III/IV non‐small cell lung cancer …

[HTML][HTML] A retrospective study of low-dose apatinib combined with S-1 in patients with advanced non-small cell lung cancer

T Zhou, C Wu, C Zhang, P Li, H Dong… - Journal of Thoracic …, 2019 - ncbi.nlm.nih.gov
Background The current regimens for advanced non-small cell lung cancer (NSCLC)
patients are deficient due to failings in standard treatments. This retrospective study aimed to …