The combination of high-density transposon-mediated mutagenesis and high-throughput
sequencing has led to significant advancements in research on essential genes, resulting in …

Essential genes refer to genes that are required by an organism to survive under specific
conditions. Studies of the minimal-gene-set for bacteria have elucidated fundamental …

Essential genes are those indispensable for the survival of an organism, and their functions
are therefore considered a foundation of life. Determination of a minimal gene set needed to …

Essential genes are genes that are indispensable to support cellular life. These genes
constitute a minimal gene set required for a living cell. We have constructed a Database of …

Background The identification of genes essential for survival is of theoretical importance in
the understanding of the minimal requirements for cellular life, and of practical importance in …

Gene essentiality has emerged as an often-asked question in the wake of bacterial genome
sequencing and a renaissance in studies of prokaryotic physiology. Genome-scale efforts at …

Rapid and accurate identification of new essential genes in under-studied microorganisms
will significantly improve our understanding of how a cell works and the ability to re-engineer …

Within the past five years genome-scale gene essentiality data sets have been published for
ten diverse bacterial species. These data are a rich source of information about cellular …

Gene essentiality is a founding concept of genetics with important implications in both
fundamental and applied research. Multiple screens have been performed over the years in …

OGEE is an Online GEne Essentiality database. To enhance our understanding of the
essentiality of genes, in OGEE we collected experimentally tested essential and non …