The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force report: serotonergic psychedelic treatments for major depressive disorder

JD Rosenblat, MI Husain, Y Lee… - The Canadian …, 2023 - journals.sagepub.com
Objective Serotonergic psychedelics are re-emerging as potential novel treatments for
several psychiatric disorders including major depressive disorder. The Canadian Network …

The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis

SB Goldberg, BT Pace, CR Nicholas, CL Raison… - Psychiatry …, 2020 - Elsevier
The current meta-analysis examined the effects of psilocybin in combination with behavioral
interventions on anxiety and depression in samples with elevated symptoms. Across four …

Psilocybin: From ancient magic to modern medicine

DE Nichols - The Journal of antibiotics, 2020 - nature.com
Abstract Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) is an indole-based
secondary metabolite produced by numerous species of mushrooms. South American Aztec …

How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change

RJ Zeifman, AC Wagner, CM Monson… - Journal of Affective …, 2023 - Elsevier
Background Psilocybin therapy is receiving attention as a mental health intervention with
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …

Psychotherapy with psilocybin for depression: systematic review

JJ Dawood Hristova, V Pérez-Jover - Behavioral Sciences, 2023 - mdpi.com
Depression is a common mental health issue that affects 280 million people in the world with
a high mortality rate, as well as being a leading cause of disability. Psychopharmacological …

Acute effects of psilocybin after escitalopram or placebo pretreatment in a randomized, double‐blind, placebo‐controlled, crossover study in healthy subjects

AM Becker, F Holze, T Grandinetti… - Clinical …, 2022 - Wiley Online Library
The psychedelic psilocybin is being investigated for the treatment of depression and anxiety.
Unclear is whether antidepressant treatments interact with psilocybin. The present study …

Effects of DMT on mental health outcomes in healthy volunteers

C Timmermann, RJ Zeifman, D Erritzoe, DJ Nutt… - Scientific Reports, 2024 - nature.com
Psilocybin, a serotonergic psychedelic, is being increasingly researched in clinical studies
for the treatment of psychiatric disorders. The relatively lengthy duration of oral psilocybin's …

Pharmacokinetics of escalating doses of oral psilocybin in healthy adults

RT Brown, CR Nicholas, NV Cozzi, MC Gassman… - Clinical …, 2017 - Springer
Introduction Psilocybin is a psychedelic tryptamine that has shown promise in recent clinical
trials for the treatment of depression and substance use disorders. This open-label study of …

[HTML][HTML] Analysis of psilocybin-assisted therapy in medicine: A narrative review

S Ziff, B Stern, G Lewis, M Majeed, VR Gorantla - Cureus, 2022 - ncbi.nlm.nih.gov
Psilocybin-containing mushrooms have been consumed by various cultures in many
different parts of the world for thousands of years. Psilocybin, a classic psychedelic, contains …

Potential therapeutic effects of psilocybin

MW Johnson, RR Griffiths - Neurotherapeutics, 2017 - Springer
Psilocybin and other 5-hydroxytryptamine 2A agonist classic psychedelics have been used
for centuries as sacraments within indigenous cultures. In the mid-twentieth century they …