Normal aortic valves are composed of valve endothelial cells (VECs) and valve interstitial
cells (VICs). VICs are the major cell population and have distinct embryonic origins in the …

These findings provide important insights into the molecular and genetic basis of aortic valve
malformations, including BAV, specifically highlighting the etiologic role of endothelial cells …

Bicuspid aortic valve (BAV) is a common congenital heart malformation frequently
associated with the development of aortic valve diseases and severe aortopathy, such as …

Bicuspid aortic valve (BAV) is the most common congenital valvular heart defect with an
overall frequency of 0.5%–1.2%. BAVs result from abnormal aortic cusp formation during …

Bicuspid aortic valve (BAV) is the most common congenital heart defect, affecting 1‐2% of
the population. It is generally diagnosed late in adulthood when deterioration of the …

The bicuspid aortic valve (BAV), a valve with two instead of three aortic leaflets, belongs to
the most prevalent congenital heart diseases in the world, occurring in 0.5-2% of the general …

Individuals with a bicuspid aortic valve (BAV) are at significantly higher risk of developing
aortic complications than individuals with tricuspid aortic valves (TAV) and defective …

Bicuspid aortic valve (BAV) is the most common congenital cardiac anomaly in humans.
Despite recent advances, the molecular basis of BAV development is poorly understood …

Although in many ways the arterial and atrioventricular valves are similar, both being
derived for the most part from endocardial cushions, we now know that the arterial valves …

Bicuspid aortic valve (BAV) patients have an increased incidence of developing aortic
dilation. Despite its importance, the pathogenesis of aortopathy in BAV is still largely …