Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare
Whole metagenome analysis has the potential to reveal functional triggers of skin diseases,
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …
Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis
Atopic dermatitis (AD) has long been associated with Staphylococcus aureus skin
colonization or infection and is typically managed with regimens that include antimicrobial …
colonization or infection and is typically managed with regimens that include antimicrobial …
Microbe-host interplay in atopic dermatitis and psoriasis
Despite recent advances in understanding microbial diversity in skin homeostasis, the
relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we …
relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we …
Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions
S Saheb Kashaf, DM Proctor, C Deming, P Saary… - Nature …, 2022 - nature.com
Human skin functions as a physical barrier to foreign pathogen invasion and houses
numerous commensals. Shifts in the human skin microbiome have been associated with …
numerous commensals. Shifts in the human skin microbiome have been associated with …
[HTML][HTML] Research techniques made simple: profiling the skin microbiota
MD Grogan, C Bartow-McKenney, L Flowers… - Journal of Investigative …, 2019 - Elsevier
Skin is colonized by microbial communities (microbiota) that participate in immune
homeostasis, development and maintenance of barrier function, and protection from …
homeostasis, development and maintenance of barrier function, and protection from …
Evolving approaches to profiling the microbiome in skin disease
Despite its harsh and dry environment, human skin is home to diverse microbes, including
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …
The intersection of microbiome and host at the skin interface: genomic-and metagenomic-based insights
EA Grice - Genome research, 2015 - genome.cshlp.org
The past two decades have been marked by a surge in research to understand the microbial
communities that live in association with the human body, in part stimulated by affordable …
communities that live in association with the human body, in part stimulated by affordable …
Microbiome dynamics of human epidermis following skin barrier disruption
PLJM Zeeuwen, J Boekhorst, EH van den Bogaard… - Genome biology, 2012 - Springer
Background Recent advances in sequencing technologies have enabled metagenomic
analyses of many human body sites. Several studies have catalogued the composition of …
analyses of many human body sites. Several studies have catalogued the composition of …
[HTML][HTML] Skin microbiome surveys are strongly influenced by experimental design
JS Meisel, GD Hannigan, AS Tyldsley… - Journal of Investigative …, 2016 - Elsevier
Culture-independent studies to characterize skin microbiota are increasingly common, due
in part to affordable and accessible sequencing and analysis platforms. Compared to culture …
in part to affordable and accessible sequencing and analysis platforms. Compared to culture …
Biogeography and individuality shape function in the human skin metagenome
J Oh, AL Byrd, C Deming, S Conlan, HH Kong… - Nature, 2014 - nature.com
The varied topography of human skin offers a unique opportunity to study how the body's
microenvironments influence the functional and taxonomic composition of microbial …
microenvironments influence the functional and taxonomic composition of microbial …
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