Biocatalysis making waves in organic chemistry

U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

The Hitchhiker's guide to biocatalysis: recent advances in the use of enzymes in organic synthesis

RA Sheldon, D Brady, ML Bode - Chemical science, 2020 - pubs.rsc.org
Enzymes are excellent catalysts that are increasingly being used in industry and academia.
This perspective is primarily aimed at synthetic organic chemists with limited experience …

Biocatalysis: landmark discoveries and applications in chemical synthesis

A O'Connell, A Barry, AJ Burke, AE Hutton… - Chemical Society …, 2024 - pubs.rsc.org
Biocatalysis has become an important tool in chemical synthesis, allowing access to
complex molecules with high levels of activity and selectivity and with low environmental …

Recent advances in biocatalytic promiscuity: hydrolase‐catalyzed reactions for nonconventional transformations

M López‐Iglesias, V Gotor‐Fernández - The Chemical Record, 2015 - Wiley Online Library
Enzymes have emerged in recent decades as ideal catalysts for synthetic transformations
under mild reaction conditions. Their capacity to accelerate a myriad of biotransformations …

Looking back: a short history of the discovery of enzymes and how they became powerful chemical tools

CM Heckmann, F Paradisi - ChemCatChem, 2020 - Wiley Online Library
Enzymatic approaches to challenges in chemical synthesis are increasingly popular and
very attractive to industry given their green nature and high efficiency compared to traditional …

Embracing nature's catalysts: a viewpoint on the future of biocatalysis

B Hauer - Acs Catalysis, 2020 - ACS Publications
Enzymes are nature's catalysts that are designed to accelerate specific reactions up to 106
times with high selectivity. 1 The enormous potential of enzymes as catalysts for organic …

Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Broadening the scope of biocatalytic C–C bond formation

LE Zetzsche, ARH Narayan - Nature Reviews Chemistry, 2020 - nature.com
Enzymes exercise impeccable control over chemoselectivity, site selectivity and
stereoselectivity in reactions they mediate, such that we have witnessed a surge in the …

[HTML][HTML] Expanding the synthetic scope of biocatalysis by enzyme discovery and protein engineering

JR Marshall, J Mangas-Sanchez, NJ Turner - Tetrahedron, 2021 - Elsevier
Despite the growing impact of enzyme catalysis in industrial chemistry, the full potential of
this technology is yet to be unlocked. Accessing new chemistries and expanding the scope …

Biocatalysis explained: from pharmaceutical to bulk chemical production

EMM Abdelraheem, H Busch, U Hanefeld… - Reaction Chemistry & …, 2019 - pubs.rsc.org
Biocatalysis is one of the most promising technologies for the sustainable synthesis of
molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to …