Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Osteoarthritis (OA) is a whole joint disease, in which thinning and disappearance of cartilage
is a critical determinant in OA progression. The rupture of cartilage homeostasis whatever its …

Structural damage of cartilage and bone tissue is a hallmark of rheumatoid arthritis (RA).
The resulting joint destruction constitutes one of the major disease consequences for …

Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide
future therapeutic strategies to modulate the disease progression. The current paradigm of …

Although cartilage degeneration characterizes human osteoarthritis (OA), changes also
involve the participation of the synovial membrane and the subchondral bone. In this review …

It is increasingly recognized that the pathogenesis of cartilage degradation in osteoarthritis
(OA) is multifactorial and involves the interactions between cartilage and its surrounding …

Osteoarthritis (OA) is the most common form of joint disease. Histopathologically, OA is
characterized by a progressive loss of articular cartilage, osteophyte formation, thickening of …

Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …

Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western
world. It affects first and foremost the articular cartilages and leads to a molecular and …