Tuberculosis (TB) is one of three major infectious diseases, and the control of TB is
becoming more difficult because of the emergence of multidrug-resistant and extensively …

Nuclear magnetic resonance (NMR) spectroscopy is an ideal platform for the metabolic
analysis of biofluids due to its high reproducibility, nondestructiveness, nonselectivity in …

With the understanding that the laboratory propagated strain of Mycobacterium tuberculosis
H37Rv is of modest virulence and is drug susceptible, in the present study, we performed a …

The pathogenic success of Mycobacterium tuberculosis (Mtb) is tightly linked to its ability to
recalibrate host metabolic processes in infected host macrophages. Since changes in …

The mechanisms whereby Mycobacterium tuberculosis (Mtb) rewires the host metabolism in
vivo are surprisingly unexplored. Here, we used three high-resolution mass spectrometry …

Although previous studies have reported the use of metabolomics for Mycobacterium
species differentiation, little is known about the potential of extracellular metabolites of …

A crucial and distinctive feature of tuberculosis infection is that Mycobacterium tuberculosis
(Mtb) resides in granulomatous lesion at various stages of disease development and …

Although tuberculosis (TB) causes more deaths than any other pathogen, most infected
individuals harbor the pathogen without signs of disease. We explored the metabolome of> …

Metabolic adaptation of Mycobacterium tuberculosis (M. tuberculosis) to microbicidal
intracellular environment of host macrophages is fundamental to its pathogenicity. However …

Although tuberculosis (TB) is a severe health problem worldwide, the current diagnostic
methods are far from optimal. Metabolomics is increasingly being used in the study of …