[HTML][HTML] Lipid peroxidation produces a diverse mixture of saturated and unsaturated aldehydes in exhaled breath that can serve as biomarkers of lung cancer—a …

SR Sutaria, SS Gori, JD Morris, Z Xie, XA Fu, MH Nantz - Metabolites, 2022 - mdpi.com
The peroxidation of unsaturated fatty acids is a widely recognized metabolic process that
creates a complex mixture of volatile organic compounds including aldehydes. Elevated …

[HTML][HTML] Exhaled aldehydes as biomarkers for lung diseases: a narrative review

MA Floss, T Fink, F Maurer, T Volk, S Kreuer… - Molecules, 2022 - mdpi.com
Breath analysis provides great potential as a fast and non-invasive diagnostic tool for
several diseases. Straight-chain aliphatic aldehydes were repeatedly detected in the breath …

Breath gas aldehydes as biomarkers of lung cancer

P Fuchs, C Loeseken, JK Schubert… - International Journal of …, 2010 - Wiley Online Library
There is experimental evidence that volatile substances in human breath can reflect
presence of neoplasma. Volatile aldehydes were determined in exhaled breath of 12 lung …

Detection of lung cancer with volatile markers in the breath

M Phillips, RN Cataneo, ARC Cummin, AJ Gagliardi… - Chest, 2003 - Elsevier
Study objectives To evaluate volatile organic compounds (VOCs) in the breath as tumor
markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products …

Determination of aldehydes in exhaled breath of patients with lung cancer by means of on-fiber-derivatisation SPME–GC/MS

D Poli, M Goldoni, M Corradi, O Acampa… - … of Chromatography B, 2010 - Elsevier
A number of volatile organic compounds (VOCs) have been identified and used in
preliminary clinical studies of the early diagnosis of lung cancer. The aim of this study was to …

[HTML][HTML] Volatile compounds in human breath: critical review and meta-analysis

T Issitt, L Wiggins, M Veysey, ST Sweeney… - Journal of Breath …, 2022 - iopscience.iop.org
Volatile compounds contained in human breath reflect the inner workings of the body. A
large number of studies have been published that link individual components of breath to …

[HTML][HTML] Exhaled volatile organic compounds as lung cancer biomarkers during one-lung ventilation

C Wang, R Dong, X Wang, A Lian, C Chi, C Ke… - Scientific reports, 2014 - nature.com
In this study, single-lung ventilation was used to detect differences in the volatile organic
compound (VOCs) profiles between lung tissues in healthy and affected lungs. In addition …

Comparison of volatile organic compounds from lung cancer patients and healthy controls—Challenges and limitations of an observational study

K Schallschmidt, R Becker, C Jung… - Journal of breath …, 2016 - iopscience.iop.org
This paper outlines the design and performance of an observational study on the profiles of
volatile organic compounds (VOCs) in the breath of 37 lung cancer patients and 23 healthy …

Identification of 2-alkenals, 4-hydroxy-2-alkenals, and 4-hydroxy-2, 6-alkadienals in exhaled breath condensate by UHPLC-HRMS and in breath by real-time HRMS

D García-Gómez, P Martínez-Lozano Sinues… - Analytical …, 2015 - ACS Publications
In recent years, breath analysis in real time has become a noninvasive alternative for the
diagnosis of diseases and for molecular fingerprinting of exhaled breath. However, the …

Detection of lung cancer: concomitant volatile organic compounds and metabolomic profiling of six cancer cell lines of different histological origins

Z Jia, H Zhang, CN Ong, A Patra, Y Lu, CT Lim… - ACS …, 2018 - ACS Publications
In recent years, there has been an extensive search for a non-invasive screening technique
for early detection of lung cancer. Volatile organic compound (VOC) analysis in exhaled …