Following the discovery of T helper 17 (TH17) cells, the past decade has witnessed a major
revision of the TH subset paradigm and substantial progress has been made in deciphering …

With the discovery of Th17 cells, the past decade has witnessed a major revision of the T
helper subset paradigm and significant progress has been made deciphering the molecular …

The characterization of the new lineage of IL-17-producing CD4+ T helper (Th17) cells has
revolutionized our current understanding of T cell-mediated immunity. Over the past five …

Abstract Interleukin 17 (IL-17)-producing helper T cells (TH17 cells) have been broadly
linked to the pathogenesis of multiple autoimmune diseases. In the few short years since the …

Autoimmune inflammatory responses and the diseases that develop as a consequence are
now thought to be driven through a novel non-Th1 pathway. IL-23, together with additional …

T‐helper 17 (Th17) cells are a new lineage of CD4+ T cells that are characterized by their
production of interleukin‐17A (IL‐17A). Recent studies show that these cells can also …

Therapeutic targeting of IL-17A and its receptor IL-17RA with antibodies has turned out to be
a tremendous success in the treatment of several autoimmune conditions. As the IL-17 …

IL-17 (interleukin-17), a hallmark cytokine of Th17 (T-helper 17) cells, plays critical roles in
host defence against bacterial and fungal infections, as well as in the pathogenesis of …

Abstract OTHER ARTICLES PUBLISHED IN THIS MINI-REVIEW SERIES ON Th17 CELLS
Induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol 2009; doi …

With all the incredible progress in scientific research over the past two decades, the trigger
of the majority of autoimmune disorders remains largely elusive. Research on the biology of …