Carcinogenesis is a multistep process involving mutation and the subsequent selective
clonal expansion of the mutated cell. Chemical and physical agents including those that …

Reactive oxygen species (ROS) are induced through a variety of endogenous and
exogenous sources. Overwhelming of antioxidant and DNA repair mechanisms in the cell by …

Carcinogenesis is a multistep process involving both mutation of critical genes and
increased cell proliferation. Over production of oxygen species (ROS) occurs from …

Cancer is a multistage and complex process characterized by molecular alterations that
underlie all three phases of its development:(i) initiation,(ii) promotion and (iii) progression …

Oxidative stress is associated with carcinogenesis. Reactive oxygen and nitrogen species
contribute to the accumulation of mutations in the genome, presumably followed by selective …

Background: Cancer is considered a major cause of death worldwide. The etiology of cancer
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …

Reactive oxygen species (ROS) are the more abundant free radicals in nature and have
been related with a number of tissue/organ injuries induced by xenobiotics, ischemia …

Chemical carcinogenesis follows a multistep process involving both mutation and increased
cell proliferation. Oxidative stress can occur through overproduction of reactive oxygen and …

Cancer in humans and animals is a multistep disease process. In this process, a single cell
can develop from an otherwise normal tissue into a malignancy that can eventually destroy …

Oxidative stress is associated with inflammation, radiation, reperfusion, and iron overload.
Epidemiological observations have shown that oxidative stress is one of the major sources …