Background: To identify immunosuppressive elements present in ovarian cancer associated
ascites. Patients and Methods: Ascites and plasma were obtained from ovarian, primary …

Epithelial ovarian cancer (EOC) is an immunogenic tumour and exploits many suppressive
ways to escape immune eradication. EOC is known to spread primarily by tumour cell …

Background The acellular fraction of epithelial ovarian cancer (EOC) ascites promotes de
novo resistance of tumor cells and thus supports the idea that tumor cells may survive in the …

Background The behavior of tumor cells is influenced by the composition of the surrounding
tumor environment. The importance of ascites in ovarian cancer (OC) progression is being …

Ovarian cancer (OC) has a specific type of metastasis, via transcoelomic, and most of the
patients are diagnosed at advanced stages with multiple tumors spread within the peritoneal …

Invasive ovarian cancer is associated with poor outcome. The presence of infiltrating
regulatory T-cells (Tregs) suppresses protective anti-tumor immune responses, and their …

Background Platinum-based combination therapy is the standard first-line treatment for
women with advanced serous epithelial ovarian carcinoma (EOC). However, about 20% will …

BACKGROUND: Considering the high mortality rate of ovarian cancer due to the absence of
curative treatment in advanced stage or at recurrence, new therapeutic strategies are …

Background Epithelial ovarian cancer (EOC) remains a highly lethal gynecological
malignancy. Ascites, an accumulation of peritoneal fluid present in one-third of patients at …

To investigate and compare the phenotype and function of lymphocytes collected from
patients harboring advanced ovarian cancer, leukocytes from peripheral blood (n= 18) …