[PDF][PDF] Targeting Gametocytes of the Malaria Parasite Plasmodium falciparum in a Functional Genomics Era: Next Steps. Pathogens 2021, 10, 346

J Chawla, J Oberstaller, JH Adams - 2021 - academia.edu
Mosquito transmission of the deadly malaria parasite Plasmodium falciparum is mediated by
mature sexual forms (gametocytes). Circulating in the vertebrate host, relatively few …

Targeting Gametocytes of the Malaria Parasite Plasmodium falciparum in a Functional Genomics Era: Next Steps

J Chawla, J Oberstaller, JH Adams - Pathogens, 2021 - mdpi.com
Mosquito transmission of the deadly malaria parasite Plasmodium falciparum is mediated by
mature sexual forms (gametocytes). Circulating in the vertebrate host, relatively few …

Targeting human transmission biology for malaria elimination

SK Nilsson, LM Childs, C Buckee, M Marti - PLoS pathogens, 2015 - journals.plos.org
Malaria remains one of the leading causes of death worldwide, despite decades of public
health efforts. The recent commitment by many endemic countries to eliminate malaria …

Phenotypic Screens Identify Genetic Factors Associated with Gametocyte Development in the Human Malaria Parasite Plasmodium falciparum

J Chawla, I Goldowitz, J Oberstaller… - Microbiology …, 2023 - Am Soc Microbiol
Transmission of the deadly malaria parasite Plasmodium falciparum from humans to
mosquitoes is achieved by specialized intraerythrocytic sexual forms called gametocytes …

A Forward Genetic Screen Identifies Genes Involved in Gametocyte Development of the Human Malaria Parasite Plasmodium falciparum.

J Chawla - 2023 - search.proquest.com
Transmission of the deadly malaria parasite Plasmodium falciparum from human to
mosquito is achieved by specialized intraerythrocytic sexual forms called gametocytes …

Biology of malaria transmission

E Meibalan, M Marti - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on Plasmodium falciparum malaria transmission …

SD Boltryk, A Passecker, A Alder… - bioRxiv, 2020 - biorxiv.org
The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of
infected humans. During each replication cycle, a small proportion of parasites commits to …

Plasmodium falciparum gametocytogenesis, dynamics, and transmission viability

RM West - 2020 - search.proquest.com
Efforts to control malaria worldwide have led to significant progress in treating and
preventing malaria, yet over 228 million infections were reported in 2018. Each infection is a …

Uncovering the genetics underlying host-parasite interactions during Plasmodium falciparum malaria transmission

M Mohammed - 2023 - diva-portal.org
In eukaryotes, cellular differentiation is often orchestrated by programmed arrays of
activation and repression of genes underlying the specific phenotypes of cell-types. To …

Revisiting gametocyte biology in malaria parasites

P Ngotho, AB Soares, F Hentzschel… - FEMS microbiology …, 2019 - academic.oup.com
Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito
vector. They are present at low levels in blood circulation and significant knowledge gaps …