Protective effect of luteolin against oxidative stress‑mediated cell injury via enhancing antioxidant systems

PDSM Fernando, DO Ko, MJ Piao… - Molecular …, 2024 - spandidos-publications.com
Physiological stress such as excessive reactive oxygen species (ROS) production may
contribute normal fibroblasts activation into cancer‑associated fibroblasts, which serve a …

Protection of cultured cortical neurons by luteolin against oxidative damage through inhibition of apoptosis and induction of heme oxygenase-1

S Kim, YW Chin, J Cho - Biological and Pharmaceutical Bulletin, 2017 - jstage.jst.go.jp
Luteolin, one of the most common flavonoids present in many types of natural products,
possesses diverse biological properties including anti-oxidant activity. In this study, we …

[HTML][HTML] Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest

H Liu, W Liu, X Zhou, C Long… - Molecular …, 2017 - spandidos-publications.com
Oxidative damage is a key factor for the pathogenesis of age‑related macular degeneration
(AMD), therefore, anti-oxidative stress is a valuable method for the prevention or treatment of …

Antioxidant and cytotoxicity effects of luteolin

J Park, KA Kang, R Zhang, MJ Piao, S Park… - Toxicological …, 2006 - dbpia.co.kr
Flavonoids are polyphenolic compounds that are ubiquitous in plants. They have been
shown to possess a variety of biological activities, such as antioxidant and anticancer …

Luteolin-induced protection of H2O2-induced apoptosis in PC12 cells and the associated pathway

P Lin, XH Tian, YS Yi, WS Jiang… - Molecular …, 2015 - spandidos-publications.com
Increasing evidence has indicated that the generation of reactive oxygen species (ROS)
contributes to H2O2-induced nerve injury. This may result in oxidative stress that leads to …

Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression

G Sun, X Sun, M Wang, J Ye, J Si, H Xu, X Meng… - Toxicology and Applied …, 2012 - Elsevier
Luteolin, a flavonoid that exhibits antioxidative properties, exerts myocardial protection
effects. However, the underlying molecular mechanisms are not yet fully understood. To …

Luteolin: a natural flavonoid enhances the survival of HUVECs against oxidative stress by modulating AMPK/PKC pathway

HC Ou, S Pandey, MY Hung, SH Huang… - The American journal …, 2019 - World Scientific
Oxidative stress has been implicated in the pathogenesis of atherosclerotic cardiovascular
diseases. Dietary supplementation of anti-oxidants has been reported to have beneficial …

Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2

D Tan, X Yu, M Chen, J Chen… - Molecular Medicine …, 2017 - spandidos-publications.com
Many studies have reported that lutein may exert its biological activities, including anti‑
inflammation, anti‑oxidase and anti‑apoptosis, through effects on reactive oxygen species …

Luteolin Alleviates Epithelial‐Mesenchymal Transformation Induced by Oxidative Injury in ARPE‐19 Cell via Nrf2 and AKT/GSK‐3β Pathway

L Chen, Y Zhu, J Zhou, R Wu, N Yang… - … Medicine and Cellular …, 2022 - Wiley Online Library
Oxidative stress plays a critical role in age‐related macular degeneration (AMD), and
epithelial‐mesenchymal transition (EMT) is involved in this process. The aim of this study …

Protective effects of luteolin against oxidative stress and mitochondrial dysfunction in endothelial cells

HI Chen, WS Hu, MY Hung, HC Ou, SH Huang… - Nutrition, Metabolism …, 2020 - Elsevier
Background and aims Luteolin is a common flavonoid that is abundantly present in various
edible plants, it is known to exhibit beneficial effects on cardiovascular system. However, the …