Vascular endothelial growth factor (VEGF) is a factor that stimulates the proliferation of
sinusoidal endothelial cells and hepatocytes during liver regeneration (LR). The present …

Background Hypoxia-inducible factor-1 alpha (HIF-1α) is one of the key regulators of
hypoxia/ischemia. MicroRNA-494 (miR-494) had cardioprotective effects against …

The regulation of HIF-1α is considered to be realized by pVHL-mediated ubiquitin-26S
proteasome pathway at a post-transcriptional level. The discovery of a class of small …

Abstract microRNA-199a (miR-199a) is a highly conserved miRNA, always deregulated in
numerous human tumors. The results of microarray analysis indicated that miR-199a was …

Abstract Background and Aim: MicroRNAs are short noncoding RNA molecules that are
responsible for the posttranscriptional regulation of target genes. The aim of this study was …

Background & Aims MicroRNAs (miRNAs) act as a regulatory mechanism on a post-
transcriptional level by repressing gene transcription/translation and play a central role in …

Hepatocellular carcinoma (HCC) is the primary and most frequently occurring type of
malignant liver cancer, accounting for 70-85% of total liver cancer cases worldwide. It has …

Hepatocellular carcinoma (HCC) is known as a frequent type of primary cancer in the liver,
and it is the third‐most common cause of cancer‐related death all over the world. However …

Background Hepatic ischemia reperfusion injury (IRI) is an inevitable clinical problem for
liver surgeons. Because microRNAs (miRNAs) participate in various hepatic …

Hepatic ischemia/reperfusion injury (IRI) is a common cause of morbidity and mortality in
liver transplantation settings and involves severe cell death and inflammatory responses …