Spatiotemporal control of CRISPR/Cas9 gene editing
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) gene editing technology, as a revolutionary breakthrough in genetic …
9 (CRISPR/Cas9) gene editing technology, as a revolutionary breakthrough in genetic …
CRISPR-Cas9 for in vivo gene therapy: Promise and hurdles
WJ Dai, LY Zhu, ZY Yan, Y Xu, QL Wang… - Molecular Therapy-Nucleic …, 2016 - cell.com
Owing to its easy-to-use and multiplexing nature, the genome editing tool CRISPR-Cas9
(clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9) …
(clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9) …
CRISPR–Cas9 in genome editing: Its function and medical applications
S Khadempar, S Familghadakchi… - Journal of cellular …, 2019 - Wiley Online Library
The targeted genome modification using RNA‐guided nucleases is associated with several
advantages such as a rapid, easy, and efficient method that not only provides the …
advantages such as a rapid, easy, and efficient method that not only provides the …
CRISPR/Cas9 therapeutics: progress and prospects
T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - … and Targeted Therapy, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential
EO Blenke, MJW Evers, E Mastrobattista… - Journal of Controlled …, 2016 - Elsevier
The CRISPR-Cas9 gene editing system has taken the biomedical science field by storm,
initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also …
initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also …
Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy
Genome editing using the clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR associated 9 (Cas9) technology is revolutionizing the study of gene …
(CRISPR)/CRISPR associated 9 (Cas9) technology is revolutionizing the study of gene …
CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
FV Jacinto, W Link, BI Ferreira - Journal of cellular and …, 2020 - Wiley Online Library
The recent development of the CRISPR/Cas9 system as an efficient and accessible
programmable genome‐editing tool has revolutionized basic science research …
programmable genome‐editing tool has revolutionized basic science research …
CRISPR/Cas9 delivery system engineering for genome editing in therapeutic applications
H Cheng, F Zhang, Y Ding - Pharmaceutics, 2021 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
Applications of CRISPR-Cas9 in Alzheimer's disease and related disorders
LM De Plano, G Calabrese, S Conoci… - International journal of …, 2022 - mdpi.com
Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's
disease represent some of the most prevalent neurodegenerative disorders afflicting …
disease represent some of the most prevalent neurodegenerative disorders afflicting …
Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity
S Aschenbrenner, SM Kallenberger, MD Hoffmann… - Science …, 2020 - science.org
The limited target specificity of CRISPR-Cas nucleases poses a challenge with respect to
their application in research and therapy. Here, we present a simple and original strategy to …
their application in research and therapy. Here, we present a simple and original strategy to …
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