Aging is accompanied by physiological changes affecting body composition and
functionality, including accumulation of fat mass at the expense of muscle mass, with effects …

Obesity and associated metabolic disorders have become highly prevalent diseases
worldwide, and the human gut microbiota, due to its influence on host energy metabolism …

Emerging evidence links the gut microbiota with several chronic diseases. However, the
relationships between metabolic syndrome (MetS), obesity and the gut microbiome are …

Accumulating literature is providing evidence that the gut microbiota is involved in metabolic
disorders, but the question of how to effectively modulate it to restore homeostasis …

Age-related alterations in human gut microbiota composition have been thoroughly
described, but a detailed functional description of the intestinal bacterial coding capacity is …

Objective An altered gut microbiota has been associated with insulin resistance, a metabolic
dysfunction consisting of cellular insulin signaling impairment. The aim of the present study …

In the present study, we characterized the distinctive signatures of the gut microbiota (GM)
from overweight/obese patients (OB), and normal-weight controls (NW), both of Sardinian …

We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects
and to determine its association with clinical variables and dietary intake. A cross-sectional …

Objective Ageing is accompanied by deterioration of multiple bodily functions and
inflammation, which collectively contribute to frailty. We and others have shown that frailty co …

Background Obesity and related co-morbidities represent a major health challenge
nowadays, with a rapidly increasing incidence worldwide. The gut microbiome has recently …